Phenotype/Genotype Correlations in Movement Disorders
- Movement Disorder
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- Enrolment target
- 2,500
- Started
- 22 October 2001
- Main results due
- Not stated
- Study sites
- 1
- Registry updated
- 28 September 2026
Can you take part?
- Ages 2 years to 100 years.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
* INCLUSION CRITERIA: * Individuals with suspected movement disorders * Family members of movement disorders patients * Ability to give informed consent or have a legally authorized representative able to give consent (for adults without consent capacity) or parent/guardian able to provide informed consent (for a child) * If unable to give informed consent, ability to give assent (for children or adults without consent capacity) * NIH Employees can participate in this study if they meet eligibility. EXCLUSION CRITERIA: * Pregnant women * Children less than 2 years of age * Employees of the Parkinson's Disease Clinic, NINDS Exclusion criteria for MRI * Presence of metal in subject s body which would make having an MRI scan unsafe, such as pacemakers, stimulators, pumps, aneurysm clips, metallic prostheses, artificial heart valves, cochlear implants or shrapnel fragments, or if subject was a welder or metal worker, since small metal fragments in the eye may be present. * Subject is uncomfortable in small closed spaces (have claustrophobia) so that they would feel uncomfortable in the MRI machine. * Unable to lie comfortably on back for up to 1 hour * Under 12 years of age There is no general exclusion for NIH employees.
What this study is about
In the sponsor’s own words, from the registry.
The goal of this protocol is to identify families with inherited movement disorders and evaluate disease manifestations to establish an accurate clinical diagnosis by using newest technological advances and investigate the underlying molecular mechanisms. Studies of inherited movement disorders in large families with good genealogical records are especially valuable. Patients with diseases of known molecular basis will be genotyped in order to investigate phenotype/genotype correlation. Patients with disease of unknown or incomplete genetic characterization will be studied with a hope of contributing to the identification of specific disease-causing genes and genetic mechanisms responsible for a specific disorder....
Study sites(1)
National Institutes of Health Clinical Center
Bethesda, Maryland, United States
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT00018889. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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