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NCT01375530From ClinicalTrials.govRecruiting

Screening Volunteers for Clinical Trials

VRC 500: Screening Volunteers for Clinical Trials of Investigational Products and Licensed Products Evaluated for Research Purposes

  • Screening

At a glance

Phase
Phase not stated
Study type
Observational
Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Enrolment target
4,000
Started
16 August 2011
Main results due
Not stated
Study sites
4
Registry updated
28 September 2026

Can you take part?

  • Ages 18 years to 60 years.
  • Open to any sex.
  • Healthy volunteers can take part.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
* INCLUSION CRITERIA:

Age: 18 years of age or older

Able and willing to complete the informed consent process

Agree to have blood and/or tissue samples collected and stored for future studies of investigational products, the immune system, and/or other medical conditions

EXCLUSION CRITERIA:

A condition in which repeated blood draws or injections pose more than minimal risk for the subject such as hemophilia, other severe coagulation disorders or significantly impaired venous access

A condition that requires active medical intervention or monitoring to avert serious danger to the participant s health or well-being

Known to be pregnant or breast-feeding

What this study is about

In the sponsor’s own words, from the registry.

Background:

\- The National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health needs healthy volunteers for vaccine clinical trials. This is a screening study that is used to identify healthy volunteers who may be eligible to participate in other clinical trials at the Vaccine Research Center that evaluate investigational vaccines, monoclonal antibodies, and injection devices. The VRC conducts studies that will allow researchers to better understand the immune system and how vaccines and monoclonal antibodies work.

Objectives:

\- To screen healthy volunteers for clinical trials at the NIAID VRC.

Eligibility:

\- Healthy people between 18 and 60 years of age. They must be available to take part in clinical trials and be able to provide blood for research studies.

Design:

* Screening for healthy volunteers to participate in clinical trials is an ongoing process. * Volunteers will be asked about their medical history, including sexual activity and drug use, and a detailed physical exam will be performed. * Blood and urine samples may be collected, and possibly other tests as needed to evaluate the volunteer's health status. * Volunteers will not receive any investigational product in this screening protocol.

Study sites(4)

  • Emory University

    Atlanta, Georgia, United States

    Completed

  • Univ of MD School of Medicine Center for Vaccine Development & Global Health

    Baltimore, Maryland, United States

    Active, not recruiting

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, United States

    Recruiting

  • University of Pennsylvania-UPenn

    Philadelphia, Pennsylvania, United States

    Completed

Showing 4 of 4 sites. 1 of the 4 sites on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT01375530. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Screening Volunteers for Clinical Trials | Trialion