National Eye Institute Biorepository for Retinal Diseases
NEI Intramural Biorepository for Retinal Diseases
- Age-Related Macular Degeneration
- Diabetic Retinopathy
- Von Hippel-Lindau Syndrome
- Retinal Disease
- Retinal Vein Occlusion
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- National Eye Institute (NEI)
- Enrolment target
- 650
- Started
- 18 June 2012
- Main results due
- Not stated
- Study sites
- 1
- Registry updated
- 28 September 2026
Can you take part?
- Ages 2 years to 120 years.
- Open to any sex.
- Healthy volunteers can take part.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
* INCLUSION CRITERIA: Participants will be eligible if they: * Have the ability to understand and sign an informed consent or have a parent/legal guardian to do so if they are minor children. * Manifest diagnosed or undiagnosed retinal disease(s), or could serve as an unaffected control suitable for comparison to participants with various retinal diseases, particularly AMD and diabetic retinopathy (taking into account matching factors such as age and past ocular history). EXCLUSION CRITERIA: Participants will not be eligible if they: * Are unable or unwilling to give informed consent that includes collection and study of at least one peripheral blood sample. * Are unable or unwilling to give informed consent that includes use of NIH medical records and clinical samples for research. * Have a systemic disease that compromises the ability to provide adequate ophthalmologic examination or treatment.
What this study is about
In the sponsor’s own words, from the registry.
Background:
\- To understand diseases of the retina and the eye, information is needed about people with and without such diseases. Researchers want to study these people and follow them over time. They also want to study body tissues and blood to understand the nature of eye disease. Studying genes, cells, and tissues may help them understand why some people get eye problems and others do not, or why some people respond to treatment while others do not. Researchers want to collect physical samples and personal data to develop a National Eye Institute database.
Objectives:
\- To collect health information and blood and tissue samples from people with and without eye diseases, to be used in research studies.
Eligibility:
* Individuals at least 2 years of age with different types of eye disease. * Healthy volunteers with no history of eye disease.
Design:
* Participants may be recruited from National Eye Institute studies or may be referred from other sources. * Participants will be screened with a physical exam and medical history. They will also have a full eye exam. Questions will be asked about family medical history, especially about eye disease. * Blood samples will be collected. Other samples, such as saliva, tears, hair, stool, and urine, may be collected as needed. Adult participants may also provide a skin sample. * Tissue or fluid from eye collected as part of eye care or treatment may also be added to the database. * No treatment will be provided as part of this study.
Study sites(1)
National Institutes of Health Clinical Center
Bethesda, Maryland, United States
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT01496625. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
Not the right study?
Answer three questions and see the studies recruiting near you, in plain language.
Find a study for me