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NCT01571531From ClinicalTrials.govRecruiting

European Multicentre Study of Human Spinal Cord Injury

European Multicentre Study of Human SCI

  • Spinal Cord Injury

At a glance

Phase
Phase not stated
Study type
Observational
Sponsor
University of Zurich
Enrolment target
8,000
Started
April 2004
Main results due
December 2026
Study sites
1
Registry updated
25 September 2026

Can you take part?

  • Aged 18 years and over.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* Single event traumatic or ischemic para- or tetraplegia
* First EMSCI assessment possible within the first 6 weeks after incidence
* Patient capable and willing of giving written informed consent

Exclusion Criteria:

* Nontraumatic para- or tetraplegia (i.e. discusprolaps, tumor, AV-malformation, myelitis) excl. single event ischemic incidences
* Pre-known dementia or severe reduction of intelligence, leading to reduced capabilities of cooperation or giving consent
* Peripheral nerve lesions above the level of lesion (i.e. plexus brachialis impairment)
* Pre-known polyneuropathy
* Severe craniocerebral injury

What this study is about

In the sponsor’s own words, from the registry.

Today there is accumulating evidence from animal experiments that regeneration can be induced after a spinal cord injury (SCI). Consequently in the near future, new therapeutic approaches to induce some regeneration will be included in the treatment of patients with SCI. The aim of this proposal is to provide the required clinical basis for the implementation of novel interventional therapies. The establishment of combined clinical, functional and neurophysiological measures for a qualitative and quantitative assessment of spinal cord function in patients with SCI at different stages during rehabilitation represents a basic requirement to monitor any significant effect of a new treatment. Therefore, several European Paraplegic Centres involved in the rehabilitation of acute traumatic SCI patients build up a close collaboration for standardised assessment. The aim is to get knowledge about the natural recovery after spinal cord lesion in a larger population of patients in the sense of a historical control group and to bring new standardised assessment tools to the clinical setting.

Study sites(1)

  • University of Zurich

    Zurich, Switzerland

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT01571531. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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European Multicentre Study of Human Spinal Cord Injury | Trialion