Screening Nasopharyngeal Carcinoma With EBV Associated Biomarkers in Zhongshan City
Searching for Early Detection Biomarkers of Nasopharyngeal Carcinoma in Zhongshan City
- Nasopharyngeal Carcinoma
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- Zhongshan People's Hospital, Guangdong, China
- Enrolment target
- 40,000
- Started
- 1 April 2020
- Main results due
- 31 December 2025
- Study sites
- 2
- Registry updated
- 29 September 2026
Can you take part?
- Ages 30 years to 69 years.
- Open to any sex.
- Healthy volunteers can take part.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Subject residents in Zhongshan City or Wuzhou City * Subject has no medical record of nasopharyngeal carcinoma * ECOG 0-2 * Subject is able to comprehend, sign, and date the written informed consent document to participate in the study. * Subject has psychical condition and well consciousness, and also accept and cooperate with the follow-up of this study. Exclusion Criteria: * Subject has heavy cardiovascular, liver or kidney disease. * Subject has contraindications to nasopharyngeal fiberoptic endoscopy.
What this study is about
In the sponsor’s own words, from the registry.
The study includes two cohorts: (1) a serological screening cohort; (2) a serological and EBV DNA screening cohort. All participants will be tested for EBNA1-IgA, VCA-IgA, BNLF2b total antibodies (P85-Ab), with additional plasma EBV DNA testing in the latter cohort. Screening positive participants will be followed up annually.
All subjects will also be followed by record linkage to Cancer Register and Population Register.
Study sites(2)
Zhongshan People's Hospital
Zhongshan, Guangdong, China
Recruiting
Wuzhou Red Cross Hospital
Wuzhou, Guangxi, China
Recruiting
Showing 2 of 2 sites. 2 of the 2 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT04085900. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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