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NCT05743933From ClinicalTrials.govRecruiting

Chongqing Adrenogenic Autonomic Cortisol Secretion Cohort Study

  • Diagnosis
  • Treatment
  • Adrenogenic Autonomic Cortisol Secretion

At a glance

Phase
Phase not stated
Study type
Observational
Sponsor
Chongqing Medical University
Enrolment target
200
Started
17 February 2023
Main results due
15 February 2033
Study sites
1
Registry updated
24 September 2026

Can you take part?

  • No age limit is stated.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* CT examination revealed adrenal nodules (maximum diameter ≥10mm);
* Serum cortisol \> 50nmol/L after 1mg dexamethasone inhibition test (1mg-DST).

Exclusion Criteria:

* Patients with primary aldosteronism (PA), pheochromocytoma, adrenal metastatic carcinoma, congenital adrenal hyperplasia (CAH), ganglionic neuroma/paraganglioma, schwannoma, adrenal hematoma and those with no definite diagnosis were evaluated by clinical and endocrine function.
* Patients with serious underlying diseases (such as liver and kidney failure, acute severe infection, etc.) that may affect the function of the hypothalamic-pituitary-adrenal axis (HPA axis); Pregnancy.
* Patients with a history of alcoholism, fatigue, trauma, infection, depression, glucocorticoid use, and other drugs affecting the function of the hypothalamic-pituitary-adrenal axis.
* Patients who are not willing to participate in and complete this study refuse to sign the written informed consent for this study.

What this study is about

In the sponsor’s own words, from the registry.

To investige the etiology, pathogenesis, diagnosis and treatment of adrenogenic autonomic cortisol secretion in Chinese adults.

Study sites(1)

  • Department of Endocrinology, Sichuan-Chongqing Joint Key Laboratory of Metabolic Vascular Diseases, Chongqing Key Laboratory of Translational Medicine in Major Metabolic Diseases, The First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT05743933. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Chongqing Adrenogenic Autonomic Cortisol Secretion Cohort Study | Trialion