Vascular MRI Evaluation in Giant Cell Arteritis (VEGA)
A Longitudinal Study of Orbital and Cranial Vessel Wall MRI in Giant Cell Arteritis by the Vascular MRI Evaluation in Giant Cell Arteritis (VEGA) Collaborative
- Giant Cell Arteritis
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- University of Pennsylvania
- Enrolment target
- 400
- Started
- 29 July 2020
- Main results due
- July 2030
- Study sites
- 4
- Registry updated
- 25 September 2026
Can you take part?
- Aged 50 years and over.
- Open to any sex.
- Healthy volunteers can take part.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Age 50 years or older * First presentation of suspected GCA * New or worsening cranial manifestations within 4 weeks of enrollment concerning for active GCA * Elevated CRP greater than 1.0 mg/dl * Plan to undergo temporal artery biopsy or ultrasound for diagnosis Exclusion Criteria: * Contra-indication to receiving MRI including: Implanted medical devices, pacemaker, and metallic foreign fragments inside body/orbits Known gadolinium allergy Women who are pregnant or nursing * Absence of cranial symptoms related to GCA (e.g., only large vessel GCA)
What this study is about
In the sponsor’s own words, from the registry.
The research study is being conducted to determine the utility of magnetic resonance imaging (MRI) in identifying inflammation of arteries supplying blood to the head, brain, and eyes. The target population includes patient with suspected giant cell arteritis (GCA; temporal arteritis).
Study sites(4)
Mayo Building and Gonda Building
Rochester, Minnesota, United States
Recruiting
3400 Civic Center Blvd
Philadelphia, Pennsylvania, United States
Recruiting
St. Joseph's Healthcare Hamilton
Hamilton, Ontario, Canada
Not yet recruiting
University Hospital Wuerzburg
Würzburg, Würzburg, Germany
Not yet recruiting
Showing 4 of 4 sites. 2 of the 4 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT05865054. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
Not the right study?
Answer three questions and see the studies recruiting near you, in plain language.
Find a study for me