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NCT06024785From ClinicalTrials.govRecruiting

Vertebropexy - Randomized-controlled Trial

Comparison of Ligamentous Fixation Technique (Vertebropexy) Versus Conventional Decompression or Fusion Surgery for Degenerative Lumbar Spinal Disease: A Randomized Controlled Trial

  • Degeneration
  • Spinal Stenosis
  • Fusion of Spine

At a glance

Phase
Phase not stated
Study type
Interventional
Sponsor
Balgrist University Hospital
Enrolment target
164
Started
16 January 2025
Main results due
1 September 2030
Study sites
1
Registry updated
28 September 2026

Can you take part?

  • Aged 18 years and over.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* Age ≥ 18 years
* Single-level or two-level lumbar surgery needed
* Indication for decompression surgery in patients with spinal canal stenosis and additional stable degenerative listhesis (without facet joint effusion ≥ 2mm)
* Indication for fusion surgery in patients with spinal canal stenosis and additional unstable degenerative listhesis (facet joint effusion ≥ 2mm), in patients with foraminal stenosis and additional degenerative listhesis, and in patients with segment degeneration of the disc
* Understanding in German language

Exclusion criteria:

* Indication for decompression and/or fusion surgery in patients with solely disc herniation, fractures, lytic listhesis, tumor
* Patients undergoing revision surgery for infection
* Patients undergoing revision surgery on the same level if bony structures have been removed (e.g. prior laminectomy or midline decompression)
* Patients undergoing revision surgery in case of prior fusion surgery
* Inability to understand the study for linguistic or cognitive reasons
* Anticipated clinical follow-up of less than 6 weeks after inclusion
* Participation in other clinical trials

What this study is about

In the sponsor’s own words, from the registry.

To assess the need for additional fusion surgery versus the risk of a revision surgery in patients with degenerative lumbar spinal disease and to assess efficacy and risk of the ligamentous fixation technique (vertebropexy)

Study sites(1)

  • Balgrist University Hospital

    Zurich, Canton of Zurich, Switzerland

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT06024785. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Vertebropexy - Randomized-controlled Trial | Trialion