NCT06037941From ClinicalTrials.govRecruiting

Using E-Nose Technology to Measure Response to Treatment in People With Malignant Pleural Mesothelioma

Breathprinting (E-Nose) Technology to Measure Response to Treatment of Malignant Pleural Mesothelioma (MPM) Through MPM-Specific Volatile Organic Compounds Detected in Exhalates

Malignant Pleural Mesothelioma

At a glance

Phase: Phase not stated
Study type: Interventional
Sponsor: Memorial Sloan Kettering Cancer Center
Enrolment target: 20
Started: 8 September 2023
Main results due: September 2027
Study sites: 7
Registry updated: 24 September 2026

Can you take part?

Ages 30 years to 85 years.
Open to any sex.
You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria

Inclusion Criteria:

* Aged 30-85 years
* No history of thoracic cancer or extrathoracic cancer potentially involving pleural metastases (i.e., breast, gastric, colon, or pancreas cancer)
* Recent diagnosis of MPM
* Documented, signed, and dated informed consent, obtained before any procedures, for the proposed research study, and signed standard surgical consent for surgical resection

Exclusion Criteria:

* Aged \<30 or \>85 years at the first outpatient visit
* History of thoracic or extrathoracic cancer that puts the subject at risk for pleural or pulmonary metastases

What this study is about

In the sponsor’s own words, from the registry.

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure how people respond to standard treatment for malignant pleural mesothelioma (MPM). The researchers will study how E-Nose breathprints change over time as people receive standard treatment for MPM. They will also look at how changes in people's E-Nose breathprints compare to changes in their standard imaging scans and in biomarkers of MPM in their blood.

Study sites(7)

Memorial Sloan Kettering Basking Ridge (Consent Only)
Basking Ridge, New Jersey, United States
Recruiting
Memorial Sloan Kettering Monmouth (Consent Only)
Middletown, New Jersey, United States
Recruiting
Memorial Sloan Kettering Bergen (Consent Only )
Montvale, New Jersey, United States
Recruiting
Memorial Sloan Kettering Cancer Center @ Suffolk-Commack (Consent Only)
Commack, New York, United States
Recruiting
Memorial Sloan Kettering Westchester (Consent Only)
Harrison, New York, United States
Recruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States
Recruiting
Memorial Sloan Kettering Nassau (Consent Only)
Uniondale, New York, United States
Recruiting

Showing 7 of 7 sites. 7 of the 7 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT06037941. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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