rTMS Treatment of Spasticity in Children With Cerebral Palsy/ Hemiplegia Due to ABI - a RCT
Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Spasticity in Children With Hemiplegic Cerebral Palsy/ Hemiplegia Due to Acquired Brain Injury - a Randomized Controlled Trial
- CP (Cerebral Palsy)
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- The University of Hong Kong
- Enrolment target
- 20
- Started
- 13 January 2024
- Main results due
- December 2029
- Study sites
- 1
- Registry updated
- 28 September 2026
Can you take part?
- Ages 4 years to 18 years.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Patients aged between 4 years and 18 years * Diagnosis of hemiplegia * Upper limb spasticity ≥ 1 * IQ ≥ 50 Exclusion Criteria: * Any contra-indications to rTMS * Severe spasticity (score of 4 or more in Ashworth scale) * Uncontrollable epilepsy * History of Botulinum toxin A injection in previous 6 months * Upper limb casting in previous 6 months
What this study is about
In the sponsor’s own words, from the registry.
This RCT aims to investigate the effect of repetitive transcranial magnatic stimulation (rTMS) in treating children with hemiplegoc cerebral palsy. The study will measure any improvement in spasticity after using contra-lesional inhibitory rTMS follow by intensive limb training.
Participants will attend a 10-day rTMS treatment sessions, follow by intensive training of the impaired limb. They will also undergo MRI scans before and after the treatment to investiagte the underlying neurophysiological mechanisms that lead to changes clinically by using TMS as well as MR-DKI. Researchers will compare the intervention group and the sham group to see if rTMS could result in improvement of participants' spasticity.
Study sites(1)
Li Ka Shing Faculty of Medicine
Hong Kong, Hong Kong, Hong Kong
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT06128746. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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