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NCT06335719From ClinicalTrials.govRecruiting

Intraoperative Electrical Stimulation to Improve Nerve Grafting Outcome

Intraoperative Brief Electrical Stimulation to Improve Cross-Face Nerve Grafting Outcomes

  • Facial Paralysis

At a glance

Phase
Phase not stated
Study type
Interventional
Sponsor
The Cleveland Clinic
Enrolment target
20
Started
1 March 2023
Main results due
31 December 2026
Study sites
1
Registry updated
28 September 2026

Can you take part?

  • Ages 18 years to 80 years.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

1. Patients 18-80 years-old with unilateral facial paralysis who are candidates for two- stage CFNG smile reanimation surgery (i.e. CFNG-driven free gracilis muscle transfer (FGMT) or dual innervation FGMT).
2. Agree to participate in the study.

Exclusion Criteria:

1. Bilateral facial paralysis
2. Age less than 18 years-old or older than 80 years-old
3. Comorbid medical condition preventing two-stage CFNG surgery

What this study is about

In the sponsor’s own words, from the registry.

A research study to find out if brief intraoperative electrical stimulation therapy improves nerve regeneration and smile outcomes following two-stage cross face nerve graft facial reanimation surgery.

Study sites(1)

  • Cleveland Clinic Foundation

    Cleveland, Ohio, United States

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT06335719. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Intraoperative Electrical Stimulation to Improve Nerve Grafting Outcome | Trialion