Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology
- Dyspnea
At a glance
- Phase
- Phase 2
- Study type
- Interventional
- Sponsor
- M.D. Anderson Cancer Center
- Enrolment target
- 150
- Started
- 11 June 2024
- Main results due
- 31 March 2030
- Study sites
- 1
- Registry updated
- 24 September 2026
Can you take part?
- Aged 18 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Diagnosis of cancer * Age 18 or older. * Admitted to a medical floor. * Dyspnea intensity at rest of at least 4 on a 0-10-point NRS (where 0 = none, 10 = worst). * Speak English or Spanish. Exclusion Criteria: * Hemodynamic instability requiring active Merit Team or ICU team involvement. * Delirium as per clinical team's assessment in the Electronic Health Record (EHR). * Severe hypoxemia (SpO2 \< 90% despite supplemental oxygen of up to 6 L/min). * Continuous positive airway pressure (CPAP) use for obstructive sleep apnea, actively using \>10 hours a day. * Respiratory failure necessitating mechanical ventilation (i.e., HFNC or NIV), and planned thoracentesis within 72 hours of enrollment. * Patients with known pregnancy.
What this study is about
In the sponsor’s own words, from the registry.
To learn about the effect of Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology (SPOT-ON) treatment on the severity of shortness of breath in patients with cancer.
Study sites(1)
MD Anderson Cancer Center
Houston, Texas, United States
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT06336642. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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