NCT06424327From ClinicalTrials.govRecruiting

A Registry for People With Lung Cancer

Pulmonary Segmentectomy for Lung Cancer: A Real-World International Registry-TSOG 108

Lung Cancer
Lung Cancer Stage I

At a glance

Phase: Phase not stated
Study type: Observational
Sponsor: Memorial Sloan Kettering Cancer Center
Enrolment target: 600
Started: 15 May 2024
Main results due: 15 May 2029
Study sites: 20
Registry updated: 24 September 2026

Can you take part?

Aged 18 years and over.
Open to any sex.
You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria

Inclusion Criteria:

* Age ≥18 years
* Patients suitable for segmentectomy, according to the treating surgeon
* Clinical Stage I with suspected NSCLC, classified preoperatively based on the AJCC TNM staging manual, 9th edition o Note: Tissue diagnosis of NSCLC is not required before enrollment. A pathologic diagnosis of NSCLC may be confirmed preoperatively with biopsy, intraoperatively with frozen section, or postoperatively on final pathology

Exclusion Criteria:

* Actively receiving lung cancer treatment or a history of lung cancer in the previous 5 years
* History of chemotherapy or radiation therapy for a previous lung cancer
* Synchronous secondary cancer in the lung or elsewhere in the body at the time of surgery
* Carcinoid tumors
* History of other malignancies within the past 3 years, with the exception of non-melanoma skin cancer, superficial bladder cancer, and carcinoma in situ of the cervix
* Actively receiving treatment for other malignancies
* Cases of lobectomy in conjunction with segmentectomy from another lobe and ≥2 segmentectomies from different lobes either en bloc or separate will be excluded from the primary analysis.

  * Multi-segmental resection from the same lobe is not a criterion for exclusion.

What this study is about

In the sponsor’s own words, from the registry.

Participants will complete questionnaires before surgery, between 2 to 4 weeks after surgery, and 6 months after surgery.

Study sites(20)

University of Arizona (Data Collection Only)
Tucson, Arizona, United States
Recruiting
University of California San Diego (Data collection)
San Diego, California, United States
Recruiting
Rush University Medical Center (Data collection only)
Chicago, Illinois, United States
Recruiting
Endeavor Health
Evanston, Illinois, United States
Recruiting
Massachusetts General Hospital Cancer Center (Data Collection Only)
Boston, Massachusetts, United States
Recruiting
Brigham and Women's Hospital (Data Collection Only)
Boston, Massachusetts, United States
Recruiting
University of Michigan (Data Collection Only)
Ann Arbor, Michigan, United States
Recruiting
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
Basking Ridge, New Jersey, United States
Recruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
Middletown, New Jersey, United States
Recruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)
Montvale, New Jersey, United States
Recruiting
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)
Commack, New York, United States
Recruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)
Harrison, New York, United States
Recruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States
Recruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)
Uniondale, New York, United States
Recruiting
Thomas Jefferson University Hospital (Data Collection Only)
Philadelphia, Pennsylvania, United States
Recruiting
ALLEGHENY HEALTH NETWORK (Data Collection Only)
Pittsburgh, Pennsylvania, United States
Recruiting
Baylor University Medical Center (Data Collection Only)
Dallas, Texas, United States
Recruiting
MD Anderson Cancer Center (Data Collection Only)
Houston, Texas, United States
Recruiting
University Health Network (Data Collection Only)
Toronto, Ontario, Canada
Recruiting
Centre Hospitalier de l'Université de Montreal (Data Collection Only)
Montreal, Quebec, Canada
Recruiting

Showing 20 of 20 sites. 20 of the 20 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT06424327. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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