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NCT06469801From ClinicalTrials.govRecruiting

ECMO ABI Detection With Hyperfine

Low-Field Bedside MRI for Detection of Acute Brain Injury in Pediatric Extracorporeal Membrane Oxygenation

  • Acute Brain Injury
  • Extracorporeal Membrane Oxygenation Complication
  • Hypoxia-Ischemia, Brain
  • Stroke, Acute

At a glance

Phase
Phase not stated
Study type
Interventional
Sponsor
Children's Mercy Hospital Kansas City
Enrolment target
40
Started
23 July 2024
Main results due
30 June 2027
Study sites
1
Registry updated
24 September 2026

Can you take part?

  • Ages 0 days to 17 years.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* Participants that will be or are admitted to the Pediatric Intensive Care Unit, Cardiac Intensive Care Unit, or the Neonatal Intensive Care Unit
* Ages 0-17 years
* Participants that are at high risk for undergoing ECMO or are currently undergoing venovenous or venoarterial ECMO

  • High risk participants include, but are not limited to:
* Undergoing cardiac surgery
* Congenital heart disease
* Congenital diaphragmatic hernia
* Refractory hypoxemic and/or hypercarbic respiratory failure
* Vasoactive-refractory shock

Exclusion Criteria:

* Pregnancy
* Any patient who has a contraindication to having an MRI
* Patients with a passive or active implant will:

  * First be reviewed on MRISafety.com to determine MR conditionality
  * If device is listed as Conditional or Unsafe for a 1.5T or a 3T, device will then be reviewed by MRI Safety Officer or MRI Physician Section chief to determine true conditionality for the portable MRI

What this study is about

In the sponsor’s own words, from the registry.

The primary objective is to characterize the prevalence and type of ABI following cannulation for pediatric patients who require ECMO support. The secondary objective is to describe the time course and rates of ABI using ultralow-field bedside MRI relative to both duration of ECMO support and clinical imaging obtained in routine care of pediatric ECMO patients.

Study sites(1)

  • Children's Mercy

    Kansas City, Missouri, United States

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT06469801. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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ECMO ABI Detection With Hyperfine | Trialion