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NCT06581042From ClinicalTrials.govRecruiting

Study to Assess Treatment Patterns and Outcomes With Upadacitinib in Adult Participants With Inflammatory Bowel Disease in Belgium

Understanding Local TReatment Patterns and Outcomes With upAdacitinib in IBD Patients in Belgium

  • Ulcerative Colitis
  • Crohn's Disease

At a glance

Phase
Phase not stated
Study type
Observational
Sponsor
AbbVie
Enrolment target
280
Started
27 September 2024
Main results due
September 2029
Study sites
11
Registry updated
23 September 2026

Can you take part?

  • Aged 18 years and over.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* Participants with a diagnosis of moderate to severe Crohn's disease or Ulcerative colitis, initiated with upadacitinib at least 12 months prior to inclusion, including participants that were initiated on upadacitinib, but later (i.e. at the moment of data collection) discontinued, or switched to another treatment.
* Participants initiating commercially available upadacitinib at the clinician's discretion as part of their routine clinical care; the decision to administer upadacitinib must be made prior to and independent of recruitment into the study
* Participants prescribed upadacitinib in accordance with the approved local label and treatment recommendations

Exclusion Criteria:

* Participants previously exposed to upadacitinib in a clinical trial or early access program
* Participants participating in interventional research (not including non-interventional
* Participants with stoma

What this study is about

In the sponsor’s own words, from the registry.

Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. Ulcerative colitis (UC) is an idiopathic, chronic, inflammatory disease affecting the colon. This study will assess the (long-term) effectiveness and safety of upadacitinib in real-world clinical practice in adult participants with moderate to severe ulcerative colitis (UC) and crohn's disease (CD).

Upadacitinib is an approved drug for treating ulcerative colitis (UC) and Crohn's disease (CD). Approximately 280 participants who are prescribed Upadacitinib by their physician in accordance with local label will be enrolled in 8 sites across Belgium.

Participants will receive upadacitinib as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 3 years.

There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice

Study sites(11)

  • Imelda Ziekenhuis /ID# 268631

    Bonheiden, Antwerpen, Belgium

    Recruiting

  • Universite Libre de Bruxelles - Hopital Erasme /ID# 268632

    Anderlecht, Brussels Capital, Belgium

    Recruiting

  • Chu De Charleroi - Hopital Civil Marie Curie /ID# 284063

    Lodelinsart, Hainaut, Belgium

    Recruiting

  • Centre Hospitalier De Wallonie Picarde - Site Notre Dame /ID# 284064

    Tournai, Hainaut, Belgium

    Recruiting

  • Groupe Sante CHC - Clinique du MontLegia /ID# 268662

    Liège, Liege, Belgium

    Recruiting

  • Ziekenhuis Oost-Limburg, Campus St.-Jan /ID# 283334

    Genk, Limburg, Belgium

    Recruiting

  • UZ Gent /ID# 268630

    Ghent, Oost-Vlaanderen, Belgium

    Recruiting

  • Vitaz /Id# 268637

    Sint-Niklaas, Oost-Vlaanderen, Belgium

    Recruiting

  • AZ Groeninge /ID# 268638

    Kortrijk, West-Vlaanderen, Belgium

    Recruiting

  • AZ-Delta. /ID# 283323

    Roeselare, West-Vlaanderen, Belgium

    Recruiting

  • CHU de Liege /ID# 267209

    Liège, Belgium

    Recruiting

Showing 11 of 11 sites. 11 of the 11 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT06581042. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Study to Assess Treatment Patterns and Outcomes With Upadacitinib in Adult Participants With Inflammatory Bowe | Trialion