Taste Alterations Study
Effects of Patient Education and Self-Management in Cancer Patients Who Experience Chemotherapy-Induced Taste Alterations
- Chemotherapy Side Effects
- Taste, Altered
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- Wake Forest University Health Sciences
- Enrolment target
- 400
- Started
- 1 December 2024
- Main results due
- November 2026
- Study sites
- 1
- Registry updated
- 24 September 2026
Can you take part?
- Aged 18 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Medical diagnosis of cancer with types limited to the top cancer types \[Note: Cancer types that are rare will be excluded\] * Initiating chemotherapy (first day/first cycle) at participating clinics * English speaking/reading (without an interpreter) Exclusion Criteria: * Substitute decision-maker (activated) * History of head/neck cancer or irradiation * Known genetic/metabolic disorder impacting taste (preexisting dysgeusia) * Known eating disorder * Receiving enteral or parenteral nutrition (special nutritional needs) * Pregnant women (unique needs) * Patients with medical orders for end of life/hospice care
What this study is about
In the sponsor’s own words, from the registry.
The main questions it aims to answer are:
1. Does completing a standard assessment increase the detection of chemotherapy induced taste changes compared with usual care (no assessment)? What TA are experienced? Are there any patterns in TA symptom occurrence based on age, sex, race/ethnicity, cancer type, chemotherapy agent, etc. 2. Do patients take action to deal with the TA? What strategies are used? Do patients in the intervention group use the assessments to select interventions? 3. Do the interventions lessen TA symptoms and maintain food intake? Is the treatment (in-depth assessment and education) more effective in lessening the intensity of TA than usual care? Which level of assessment is needed to support symptom management to reduce symptom severity?
Participants will:
Complete baseline assessment before starting their initial chemotherapy infusion (all patients) Participate in baseline patient education based on assigned intervention (usual care vs. treatment) Engage in TA management between chemotherapy infusion clinic visits based on education Visit the clinic for chemotherapy infusions as scheduled; Complete TA assessments and reporting based on intervention; Work with nurse coaches to answer questions and help with the intervention.
Complete study data collection on the 4th chemotherapy cycle (but continue intervention) Complete final data collection at 6 months
Study sites(1)
Advocate Illinois Masonic Medical Center
Chicago, Illinois, United States
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT06669416. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
Not the right study?
Answer three questions and see the studies recruiting near you, in plain language.
Find a study for me