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NCT06724406From ClinicalTrials.govRecruiting

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing): Optimization and Evaluation Using Multiphase Optimization Strategy (MOST) and Social Network Analysis (SNA)

  • Obesity and Overweight
  • Diabetes Mellitus
  • Weight Loss
  • Behavior Change

At a glance

Phase
Phase not stated
Study type
Interventional
Sponsor
University of North Carolina, Chapel Hill
Enrolment target
256
Started
3 February 2025
Main results due
31 December 2028
Study sites
1
Registry updated
29 September 2026

Can you take part?

  • Ages 18 years to 75 years.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* self-identified as Black or African American (Index participant)
* BMI equal to greater than 30 kg/m\^2 (Index); BMI equal to greater than 27.5 kg/m\^2 (family partner)
* have a partner/family member willing to enroll in the study and must share a mutual goal of achieving weight loss
* English speaking
* ages 18-75
* any gender
* have access to and be able to use a smartphone, tablet, or computer that has web-access (this is required for data collection and some program components being tested)
* able to make changes to the food you eat

Exclusion Criteria:

* planning to move out of the area with the next 8-9 months
* participation in an intensive weight loss program (more than 12 visits) in the prior 12 months
* type 1 diabetes
* significant psychiatric illness, defined as depression or other major psychiatric illness not considered reasonably managed by counseling, medication, or both
* had bariatric surgery (surgery for weight loss) in the last 2 years or considering bariatric surgery in the next 8-9 months
* using or in the prior 3 months taking prescription weight loss medications, or planning to start medications intentionally for weight loss
* lost more than 20 pounds of body weight in last 6 months
* are pregnant or planning to get pregnant in the next 8-9 months
* are breastfeeding an infant less than 3 months old
* alcohol or substance abuse, defined as alcohol or substance use that interferes with work activities and/or has had a major negative impact on family/social function, the latter defined as more than 2 episodes per month.
* malignancy other than non-melanoma skin cancer, unless considered cured \> 5 years ago. Exceptions include 1) men with localized prostate cancer (treated with usual modalities or managed with "active surveillance"), and 2) postmenopausal women receiving adjuvant endocrine therapy (e.g., aromatase inhibitor) for non-metastatic, hormone receptor-positive breast cancer
* self-report of advanced kidney disease (estimated glomerular filtration rate (GFR) \< 30 mL/min)

What this study is about

In the sponsor’s own words, from the registry.

The goal of this clinical trial is to learn the best combination of family components that yields optimal weight loss among Black adults. The main question it aims to answer is:

What combination of four family components in combination with a standard behavioral weight loss program yields optimal weight loss among Black adults? Researchers will compare different combinations of family skills components (communication content, cohesion content, number of sessions, and mode of delivery) to see the best weight loss.

Participants will:

* Participate in a 6-month behavioral weight loss intervention * Attend core weight loss in-person group sessions, and dyad based family sessions * Keep track of weight, dietary intake and physical activity

Study sites(1)

  • University of North Carolina at Chapel Hill

    Chapel Hill, North Carolina, United States

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT06724406. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing) | Trialion