Vancomycin Reduction Practices (VRP) in the NICU
Implementing Vancomycin Reducing Practices (VRP) in Preterm Infants
- Antibiotic Stewardship
- Neonatal Sepsis, Late-Onset
- Vancomycin
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- Children's Hospital of Philadelphia
- Enrolment target
- 13
- Started
- 2 June 2025
- Main results due
- September 2027
- Study sites
- 13
- Registry updated
- 24 September 2026
Can you take part?
- Aged 18 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Level III NICU * Affiliated with Kaiser Permanente Northern California (KPNC) or Children's Hospital of Philadelphia Newborn Care Network (CNBCN) * Recruited by study team Exclusion Criteria: * Site not recruited for the study
What this study is about
In the sponsor’s own words, from the registry.
This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). Sites will be recruited and randomized to receive either external facilitation or no external facilitation to assess the effect on center-level fidelity to the core components of VRP implementation. Interventions available to both study arms are directed at hospital staff and includes identification of local champions, educational outreach, unit-level audit \& feedback, and use of a clinical decision support tool.
Study sites(13)
Kaiser Permanente Modesto Medical Center
Modesto, California, United States
Recruiting
Kaiser Permanente East Bay - Oakland Medical Center
Oakland, California, United States
Recruiting
Kaiser Permanente Roseville Medical Center
Roseville, California, United States
Recruiting
Kaiser Permanente San Francisco Medical Center
San Francisco, California, United States
Recruiting
Kaiser Permanente San Leandro Medical Center
San Leandro, California, United States
Recruiting
Kaiser Permanente Santa Clara Medical Center
Santa Clara, California, United States
Recruiting
Kaiser Permanente Walnut Creek Medical Center
Walnut Creek, California, United States
Recruiting
Medical Center of Princeton
Plainsboro, New Jersey, United States
Recruiting
Virtua Voorhees
Voorhees Township, New Jersey, United States
Recruiting
Lancaster General Hospital
Lancaster, Pennsylvania, United States
Recruiting
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States
Recruiting
Pennsylvania Hospital
Philadelphia, Pennsylvania, United States
Recruiting
Chester County Hospital
West Chester, Pennsylvania, United States
Recruiting
Showing 13 of 13 sites. 13 of the 13 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT06772675. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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