NCT06777368From ClinicalTrials.govRecruiting

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

Aortic Stenosis

At a glance

Phase: Phase not stated
Study type: Observational
Sponsor: Medtronic Cardiovascular
Enrolment target: 225
Started: 6 February 2025
Main results due: November 2027
Study sites: 71
Registry updated: 24 September 2026

Can you take part?

Ages 18 years to 105 years.
Open to any sex.
You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria

Inclusion Criteria:

* BVF of a TAV (either Medtronic or Edwards) requiring redo TAVR

Exclusion Criteria:

* BVF due solely to paravalvular regurgitation
* Active endocarditis
* Untreated acute valve thrombosis
* Life-expectancy less than 1-year
* Subject is less than legal age of consent, legally incompetent, or otherwise vulnerable
* Participating in another study that may influence the outcome of this study

What this study is about

In the sponsor’s own words, from the registry.

The purpose of this study is to generate clinical evidence on valve safety and performance in subjects treated by redo Transcatheter Aortic Valve Replacement (TAVR).

Study sites(71)

University of Alabama at Birmingham
Birmingham, Alabama, United States
Recruiting
Abrazo Arizona Heart Hospital
Phoenix, Arizona, United States
Recruiting
Tucson Medical Center
Tucson, Arizona, United States
Withdrawn
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States
Recruiting
Sutter Heatlh
Sacramento, California, United States
Recruiting
Kaiser Permanente Northern California
Sacramento, California, United States
Recruiting
Stanford Hospital & Clinics
Stanford, California, United States
Recruiting
Los Robles Regional Medical Center
Thousand Oaks, California, United States
Recruiting
Medical Center of the Rockies
Loveland, Colorado, United States
Recruiting
Hartford Hospital
Hartford, Connecticut, United States
Recruiting
Yale New Haven Hospital
New Haven, Connecticut, United States
Recruiting
MedStar Washington Medical Center
Washington D.C., District of Columbia, United States
Recruiting
Morton Plant Hospital
Clearwater, Florida, United States
Recruiting
HealthPark Medical Center, Lee Memorial Health
Fort Myers, Florida, United States
Recruiting
Orlando Health/Orlando Regional Medical Center
Orlando, Florida, United States
Recruiting
Tampa General/USF
Tampa, Florida, United States
Recruiting
Parkview Health
Fort Wayne, Indiana, United States
Recruiting
Saint Vincent Heart Center of Indiana
Indianapolis, Indiana, United States
Recruiting
MercyOne Iowa Heart Center
Des Moines, Iowa, United States
Recruiting
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States
Recruiting
The University of Kansas
Kansas City, Kansas, United States
Recruiting
Ascension Via Christi St. Francis
Wichita, Kansas, United States
Recruiting
Maine Medical Center
Portland, Maine, United States
Recruiting
Medstar Union Memorial Hospital
Baltimore, Maryland, United States
Recruiting
The Johns Hopkins Hospital
Baltimore, Maryland, United States
Recruiting
Massachusetts General Hospital
Boston, Massachusetts, United States
Recruiting
Brigham and Women's Hospital
Boston, Massachusetts, United States
Recruiting
University of Michigan Health
Ann Arbor, Michigan, United States
Recruiting
Henry Ford Hospital
Detroit, Michigan, United States
Recruiting
Corewell Health (Spectrum)
Grand Rapids, Michigan, United States
Recruiting
Abbott Northwestern/Minneapolis Heart
Minneapolis, Minnesota, United States
Recruiting
Mayo Clinic
Rochester, Minnesota, United States
Recruiting
CentraCare Heart and Vascular Center
Saint Cloud, Minnesota, United States
Recruiting
St. Luke's Hospital of Kansas City
Kansas City, Missouri, United States
Recruiting
Providence Saint Patrick Hospital
Missoula, Montana, United States
Recruiting
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States
Recruiting
Catholic Medical Center
Manchester, New Hampshire, United States
Recruiting
Jersey Shore University Medical Center
Neptune City, New Jersey, United States
Recruiting
The Valley Hospital
Paramus, New Jersey, United States
Recruiting
Buffalo General Medical Center
Buffalo, New York, United States
Recruiting
Northwell Health
Manhasset, New York, United States
Recruiting
NYU Langone Medical Center
New York, New York, United States
Recruiting
Mount Sinai Hospital
New York, New York, United States
Recruiting
Saint Francis Hospital
Roslyn, New York, United States
Recruiting
Montefiore Medical Center
The Bronx, New York, United States
Recruiting
Astrium Health Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, United States
Recruiting
The Christ Hospital
Cincinnati, Ohio, United States
Recruiting
University Hospitals of Cleveland Medical Center
Cleveland, Ohio, United States
Recruiting
OhioHealth Riverside Methodist Hospital
Columbus, Ohio, United States
Recruiting
Oklahoma Heart Hospital
Oklahoma City, Oklahoma, United States
Recruiting
Providence Saint Vincent Medical Center
Portland, Oregon, United States
Recruiting
Lehigh Valley Hospital
Allentown, Pennsylvania, United States
Recruiting
UPMC Pinnacle
Mechanicsburg, Pennsylvania, United States
Recruiting
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States
Recruiting
UPMC Presbyterian
Pittsburgh, Pennsylvania, United States
Recruiting
Lankenau Medical Center
Wynnewood, Pennsylvania, United States
Recruiting
TriStar Centennial Medical Center
Nashville, Tennessee, United States
Recruiting
St. Thomas West Hospital
Nashville, Tennessee, United States
Recruiting
Ascension Seton Medical Center Austin
Austin, Texas, United States
Recruiting
Heart Hospital of Austin
Austin, Texas, United States
Recruiting

Showing 60 of 71 sites — filter to narrow it down. 70 of the 71 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT06777368. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

Not the right study?

Answer three questions and see the studies recruiting near you, in plain language.

Find a study for me