Rehabilitation Exercise and Education of Airway Clearance Technique in NTM-PD: A Prospective Cohort Study
Rehabilitation Exercise and Education of Airway Clearance Technique in Nontuberculous Mycobacterial Pulmonary Disease: A Prospective Cohort Study
- Nontuberculous Mycobacterial Pulmonary Disease
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- Seoul National University Bundang Hospital
- Enrolment target
- 500
- Started
- 21 April 2025
- Main results due
- 25 November 2028
- Study sites
- 2
- Registry updated
- 28 September 2026
Can you take part?
- Aged 20 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Age 20 years or older at the time of enrollment. * Diagnosis of nontuberculous mycobacterial pulmonary disease (NTM-PD) according to the 2020 American Thoracic Society (ATS) guidelines. * Identification of clinically significant NTM species, including: Mycobacterium avium / Mycobacterium intracellulare / Mycobacterium abscessus / Mycobacterium massiliense / Mycobacterium kansasii / * Able to undergo pulmonary rehabilitation and airway clearance training as part of the study protocol. * Willing to provide written informed consent to participate in the study. Exclusion Criteria: * Currently pregnant or actively breastfeeding. * Unable to participate in pulmonary rehabilitation due to severe mobility impairment or neuromuscular disorders. * History of massive hemoptysis or other medical conditions where airway clearance techniques may be contraindicated.
What this study is about
In the sponsor’s own words, from the registry.
* The goal of this observational study is to evaluate the effects of pulmonary rehabilitation and airway clearance education in adults with nontuberculous mycobacterial pulmonary disease (NTM-PD). The main questions it aims to answer are:
* Does pulmonary rehabilitation and airway clearance training improve lung function, symptom relief, and quality of life in patients with NTM-PD? * Does this non-pharmacological intervention contribute to better sputum culture conversion rates? * Participants will:
* Undergo pulmonary rehabilitation and airway clearance training over an 8-week period (biweekly sessions). * Receive evaluations at baseline, during the intervention, and follow-up assessments at 2 months, 6 months, and final study visit. * Undergo tests including pulmonary function tests (PFT), symptom assessments, bacteriologic evaluations, radiographic imaging (CT/X-ray), and quality of life surveys (EQ-5D-5L, CAT score). * This study aims to provide clinical evidence supporting the role of non-pharmacological treatments in the management of NTM-PD, potentially informing future treatment guidelines and improving patient outcomes.
Study sites(2)
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Recruiting
Taipei Veterans General Hospital
Taipei, Beitou Dist, Taiwan
Recruiting
Showing 2 of 2 sites. 2 of the 2 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT06838442. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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