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NCT06926153From ClinicalTrials.govRecruiting

Interventional Study on Smoking Reduction in Psychiatry

Evaluation of an Intervention to Reduce Smoking Among Mental Health Users Treated in Ambulatory Psychiatry

  • Tobacco Addiction

At a glance

Phase
Phase not stated
Study type
Interventional
Sponsor
GCS-CCOMS
Enrolment target
6,500
Started
15 January 2025
Main results due
15 July 2026
Study sites
22
Registry updated
28 September 2026

Can you take part?

  • Aged 18 years and over.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* Regular smokers (at least one cigarette per day)
* Followed in psychiatric ambulatory care at one of the participating sectors' CMPs
* Adults (18 years or older)
* Covered by the statuary health insurance
* Who gave their informed consent to participate to the study

Exclusion Criteria:

* Users under guardianship or legal protection,
* Psychological state incompatible with completing the questionnaire,
* Persons with no command or understanding of the French language

What this study is about

In the sponsor’s own words, from the registry.

The smoking rate among people with mental disorders is higher than in the general population. Greater exposure to the harmful effects of tobacco partly explains the major inequality in life expectancy observed among people with mental disorders who, depending on the disorder and the study, live 10 to 25 years less than the general population, a gap mainly due to the occurrence of cardiovascular and respiratory pathologies, notably bronchial cancers. However, tobacco reduction actions specifically targeting these people remain insufficiently developed, particularly in psychiatry where this addiction is often banalized and its treatment neglected.

The objective of this study is to evaluate an intervention ('Tabapsy') co-constructed with mental health services users, mental health professionals, and general practitioners and targeting adult patients followed in ambulatory psychiatry. The main objective is to evaluate the effectiveness of the intervention on short-term smoking cessation (cessation for at least 7 days) among regular smokers at 3 months. Secondary objectives include evaluation of its cost-effectiveness and implementation. To this end, a national cluster-randomized controlled study will be carried out, supplemented by qualitative interviews to study the implementation of the intervention.

Study sites(22)

  • Public mental health establishment of Lille Metropole (59G16-G17)

    Armentières, France

    Completed

  • Public mental health establishment of Lille Metropole (59G21)

    Armentières, France

    Completed

  • Flanders public mental health establishment (59G05/06)

    Bailleul, France

    Completed

  • Barthelemy Durand public health establishment (91G05)

    Étampes, France

    Recruiting

  • Psychotherapeutic center of Nancy (54G02-06)

    Laxou, France

    Completed

  • University Hospital Center of Lille (59G08)

    Lille, France

    Withdrawn

  • Hospital Care Center of Nanterre (92G10)

    Nanterre, France

    Completed

  • University Hospital Group Paris Neurosciences & Psychiatry (75G04)

    Paris, France

    Completed

  • Hospital Center of Rouffach (68G02/03)

    Rouffach, France

    Completed

  • Hospital Center of Rouffach (68G08/09)

    Rouffach, France

    Completed

  • Hospital Center of Rouffach (Pôle LTD - 68G04/05)

    Rouffach, France

    Completed

  • Hospitals of Paris Est Val de Marne (94G01)

    Saint-Maurice, France

    Completed

  • Hospitals of Paris Est Val de Marne (94G16)

    Saint-Maurice, France

    Completed

  • Hospitals of Paris Est Val de Marne (Paris 11)

    Saint-Maurice, France

    Completed

  • Hospitals of Paris Est Val de Marne (Paris 12)

    Saint-Maurice, France

    Completed

  • Hospitals of Paris Est Val de Marne (Paris Centre)

    Saint-Maurice, France

    Completed

  • Public mental health establishment of Val de Lys Artois (62G09)

    Saint-Venant, France

    Completed

  • Public mental health establishment of Val de Lys Artois (62G12)

    Saint-Venant, France

    Completed

  • Public mental health establishment of Val de Lys Artois (Pôle du Ternois)

    Saint-Venant, France

    Completed

  • Public mental health establishment of Guadeloupe (96G01)

    Saint-Claude, Guadeloupe

    Recruiting

  • Public mental health establishment of Guadeloupe (96G06)

    Saint-Claude, Guadeloupe

    Recruiting

  • Public mental health establishment of Reunion Island (Pôle Nord)

    Saint-Paul, Reunion

    Completed

Showing 22 of 22 sites. 3 of the 22 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT06926153. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Interventional Study on Smoking Reduction in Psychiatry | Trialion