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NCT07106593From ClinicalTrials.govRecruiting

Treatment for PTSD and Tinnitus

Treatment of TBI-Related Tinnitus and Comorbid PTSD: Examination of Neurobiological Markers Related to Symptom Improvement

  • PTSD - Post Traumatic Stress Disorder
  • Posttraumatic Stress Disorder (PTSD)
  • Tinnitus

At a glance

Phase
Phase not stated
Study type
Interventional
Sponsor
The University of Texas Health Science Center at San Antonio
Enrolment target
160
Started
8 August 2025
Main results due
August 2028
Study sites
1
Registry updated
25 September 2026

Can you take part?

  • Aged 18 years and over.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* Adult male and female active duty military personnel and veterans seeking treatment for PTSD
* Diagnosis of PTSD
* Person has experienced at least one mild traumatic brain injury (concussion)
* Ability to speak and read English
* Stable on any psychotropic medications
* Meets criteria for chronic subjective and bothersome tinnitus
* Chronic tinnitus is at least possibly related to head injury

Exclusion Criteria:

* Currently receiving other talk therapies
* Severe hearing loss that would prevent the participant from benefiting from therapy
* Current severe suicidal ideation
* Psychiatric hospitalization in the last 12 months
* Moderate to severe substance use that would prevent the participant form benefiting from therapy
* Current manic episode or psychotic symptoms requiring immediate stabilization or hospitalization
* Significant cognitive impairment
* Moderate to severe brain damage
* Neurobiological disorders
* Temporomandibular joint disorders and/or Meniere's disease that cause acute pain

What this study is about

In the sponsor’s own words, from the registry.

In this study, researchers are examining the best sequence of interventions for posttraumatic stress disorder (PTSD) and tinnitus. Participants will either receive psychotherapy for PTSD first (Cognitive Processing Therapy; CPT), followed by treatment for tinnitus (Cognitive Behavioral Therapy for Tinnitus; CBT-t); or vice-versa. We also aim to identify changes in brain functioning after receiving therapy.

Study sites(1)

  • The University of Texas Health Science Center at San Antonio

    San Antonio, Texas, United States

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT07106593. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Treatment for PTSD and Tinnitus | Trialion