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NCT07182240From ClinicalTrials.govRecruiting

Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Margins of Basal Cell Carcinomas

  • Basal Cell Carcinoma

At a glance

Phase
Phase not stated
Study type
Interventional
Sponsor
Roswell Park Cancer Institute
Enrolment target
60
Started
22 December 2025
Main results due
22 June 2027
Study sites
1
Registry updated
24 September 2026

Can you take part?

  • Aged 18 years and over.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* Age ≥ 18 years
* Participant must understand the investigational nature of this study and provide written consent prior to receiving any study-related procedure.
* Participant must be clinically eligible for Mohs surgery as determined by their referring dermatologist and the Mohs surgeon.
* The participant must have a BCC with superficial histology or a BCC with multiple histological features that also include superficial histology, which is appropriate for Mohs surgery.

Exclusion Criteria:

* Known or reported allergy to mineral oil, the optical agent used during imaging.
* Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements.
* . Any condition which in the investigator's opinion deems the subject an unsuitable candidate to undergo imaging procedure.
* Unwilling or unable to follow protocol requirements

What this study is about

In the sponsor’s own words, from the registry.

To assess the feasibility and provide information on the utility of noninvasive line field confocal optical coherence tomography (LC-OCT) for the presurgical assessment of Mohs micrographic surgery sites in patients undergoing removal of cutaneous basal cell carcinomas (BCC).

Study sites(1)

  • Roswell Park Comprehensive Cancer Center

    Buffalo, New York, United States

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT07182240. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Pilot Study of Line-Field Confocal Optical Coherence Tomography for Detection of Mohs Micrographic Surgery Mar | Trialion