Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants
Clinical Evaluation of Low Contrast Defocus Curves, Low Light Photic Phenomena, and Dysphotopsia Profiles in Pseudophakic Patients
- Dysphotopsia
- Posterior Capsule Opacification
- Visual Acuity
- Visual Function
- Contrast Sensitivity
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- Dr. Daniel H. Chang, MD
- Enrolment target
- 120
- Started
- 24 September 2025
- Main results due
- December 2026
- Study sites
- 1
- Registry updated
- 25 September 2026
Can you take part?
- Aged 22 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Minimum 22 years of age * Bilateral pseudophakia, at least 3 months postoperative from IOL implantation, with one of the study IOL models in at least one eye. * Availability, willingness, and sufficient cognitive awareness to comply with examination procedures * Signed informed consent and HIPAA authorization or equivalent documentation necessary to comply with applicable privacy laws pertaining to medical treatment in the governing countries * Ability to understand and respond to a questionnaire in English Exclusion Criteria: * Any clinically significant pupil abnormalities (non-reactive, fixed pupils, or abnormally shaped pupils. * Inability to focus or fixate for prolonged periods of time (e.g., due to strabismus, nystagmus, etc.) * Uncorrected distance visual acuity worse than 20/25 in either eye * Prior corneal refractive surgery (LASIK, LASEK, RK, PRK, etc.) or intraocular surgery. Note: Prophylactic peripheral iridotomies and peripheral laser retinal repairs that, in the opinion of the investigator will not confound study outcomes are acceptable. * Posterior capsular opacification with grading worse than 1+ * Ocular findings that may, in the opinion of the investigator, affect vision and/or contrast sensitivity
What this study is about
In the sponsor’s own words, from the registry.
The goal of this clinical investigation is to evaluate visual acuity and contrast sensitivity in low lighting conditions using several different testing devices, and measure nighttime side effects of intraocular lens (IOL) implants after cataract surgery.
Researchers will compare the results for three different types of IOLs to see how each lens contributes to overall visual function, patient experience and satisfaction.
Participants will:
* Complete two different questionnaires about their current vision * Undergo visual testing using several different devices
Study sites(1)
Empire Eye and Laser Center
Bakersfield, California, United States
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07213167. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
Not the right study?
Answer three questions and see the studies recruiting near you, in plain language.
Find a study for me