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NCT07229963From ClinicalTrials.govRecruiting

Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults

Postprandial Cardiometabolic Effects of Interrupting Sedentary Behavior With Exercise of Varying Intensity in Healthy Overweight Adults

  • Cardiovascular Risk Markers
  • Postprandial Metabolism
  • Exercise Physiology
  • Substrate Oxidation

At a glance

Phase
Phase not stated
Study type
Interventional
Sponsor
Hacettepe University
Enrolment target
18
Started
1 September 2026
Main results due
20 November 2026
Study sites
1
Registry updated
24 September 2026

Can you take part?

  • Ages 30 years to 45 years.
  • Open to any sex.
  • Healthy volunteers can take part.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria

* Being physically inactive (not doing at least 150 minutes/week of structured exercise).
* Being sedentary (having a daily sedentary time/day for \>7 hours).
* Having a BMI between 25 and 29.9 kg/m2.
* Having a history of regular menstrual cycles for female participants.
* Having medical examination approval.

Exclusion Criteria

* Taking any acute or chronic medication or supplement that may affect metabolism.
* Having an acute or chronic illness that limits exercise (musculoskeletal problems, cardiovascular disorders, respiratory problems, etc.).
* Consuming tobacco products.
* Meeting 3 or more of the metabolic syndrome criteria (waist circumference of 102 cm or more in men, 88 cm or more in women, triglyceride level of 150 mg/dL or higher, HDL cholesterol level below 40 mg/dL in men and 50 mg/dL in women, blood pressure of 130/85 mmHg or higher, fasting blood glucose level of 100 mg/dL (5.6 mg/L) or higher).

What this study is about

In the sponsor’s own words, from the registry.

The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk markers for cardiometabolic diseases; and (2) to assess substrate oxidation during this period in order to identify which exercise condition promotes the greatest increase in fat oxidation.

Study sites(1)

  • Hacettepe Sports Science Faculty, Hacettepe Beytepe Clinic

    Ankara, Beytepe, Turkey (Türkiye)

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT07229963. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults | Trialion