Efficacy of CAD in Screening Colonoscopy to Reduce the Risk of Advanced Adenoma at 3 Years.

Inclusion Criteria:

* Patients over 18 years of age with indication for colonoscopy as part of a screening program, after a positive immunological (FIT) test, and/or for personal or family history of colorectal cancer and/or personal history of colonic adenomas and/or sessile serrated polyp,
* Written informed consent signed
* Patients covered by a health-care insurance.

Exclusion Criteria:

* Failed complete colonoscopy, defined by the absence of cecal intubation or identification of the terminal ileum.
* Inadequate bowel preparation (Boston bowel preparation score \< 6, and/or least at one part of colon with score ≤ 1)
* An infiltrative tumor was diagnosed during colonoscope insertion time, not accessible to endoscopic resection and likely to require surgical management (a procedure where part of the colon may need to be removed).
* Patient under guardianship or protection
* Pregnant women
* Not fluent in French or illiterate
* Personal history of inflammatory bowel disease
* Personal history of genetic predisposition of CRC
* Personal history of major colorectal surgery involving total or subtotal colectomy