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NCT07307612From ClinicalTrials.govRecruiting

High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants

Improving Lung Health in Premature Babies Through Early Nutrition: The More & Early Nutritional Delivery for Bronchopulmonary Dysplasia (MEND-BPD) Trial

  • Extreme Prematurity
  • Enteral Nutrition
  • Bronchopulmonary Dysplasia

At a glance

Phase
Phase 1
Study type
Interventional
Sponsor
University of Alabama at Birmingham
Enrolment target
150
Started
21 September 2026
Main results due
31 March 2029
Study sites
1
Registry updated
24 September 2026

Can you take part?

  • Ages 1 day to 3 days.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* Gestational age ≤ 28 weeks of gestation
* Postnatal age \< 72 hours

Exclusion Criteria:

* Congenital malformations
* Chromosomal anomalies
* Terminal illness needing to limit or withhold support

What this study is about

In the sponsor’s own words, from the registry.

This Phase II, parallel-group, masked, randomized clinical trial aims to evaluate whether a DHA/ARA-enriched, fortified human milk diet administered during the first 14 days of life reduces respiratory morbidity and improves lung function in extremely preterm (EPT) infants (born at ≤28 weeks gestation).

Study sites(1)

  • University of Alabama at Birmingham

    Birmingham, Alabama, United States

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT07307612. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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High-energy Human Milk Diets in the First Two Weeks After Birth to Reduce BPD in Extremely Preterm Infants | Trialion