Aspiration Thrombectomy Using the Symphony or Prodigy System
Long-Term CLinical Evaluation of Aspiration ThRombectomy Using the Symphony or ProdIgy Thrombectomy System - CLEAR-IT
- Arterial Thromboembolism
- Venous Thromboembolism
- Pulmonary Embolism
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- Imperative Care, Inc.
- Enrolment target
- 750
- Started
- 13 February 2026
- Main results due
- March 2030
- Study sites
- 10
- Registry updated
- 25 September 2026
Can you take part?
- Aged 18 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: 1. Subject is ≥ 18 years of age 2. Subject is willing and able to comply with the follow-up schedule specified in this protocol 3. Subject is willing and able to provide written informed consent prior to any study-related data collection 4. Subject has a planned procedure, involving the use of Imperative Care vascular devices within their intended use Exclusion Criteria: 1. Subjects with any contraindications per the applicable Instructions for Use 2. Subject with life expectancy of less than 1 year 3. In the opinion of the Investigator, the patient is not a suitable candidate for intervention with Imperative Care devices 4. Subject who may be unable to complete study follow-up 5. Peripheral Venous Cohort ONLY: Presence of thrombus extending more than 2 cm into the IVC on imaging
What this study is about
In the sponsor’s own words, from the registry.
The study is designed to evaluate the short-term and long-term clinical performance and safety of the Symphony and Prodigy thrombectomy systems used in endovascular procedures across the peripheral or pulmonary vasculature.
Study sites(10)
Huntsville Hospital
Huntsville, Alabama, United States
Recruiting
HCA Florida Memorial Hospital
Jacksonville, Florida, United States
Recruiting
BayCare Health - St. Joseph Hospital
Tampa, Florida, United States
Recruiting
Midwest Cardiovascular Institute
Naperville, Illinois, United States
Recruiting
Profound Research
Munster, Indiana, United States
Recruiting
Henry Ford Hospital
Detroit, Michigan, United States
Recruiting
University At Buffalo
Buffalo, New York, United States
Recruiting
Mount Sinai Hospital
New York, New York, United States
Recruiting
Mercy Health
Cincinnati, Ohio, United States
Recruiting
Sentara Norfolk General Hospital
Norfolk, Virginia, United States
Recruiting
Showing 10 of 10 sites. 10 of the 10 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07350499. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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