Belgian Lung Function Study
Belgian Lung Function Study: Personalised Longitudinal Lung Function Analysis as a Marker of Disease Progression
- Chronic Respiratory Diseases
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- KU Leuven
- Enrolment target
- 5,000
- Started
- 25 March 2026
- Main results due
- 1 March 2029
- Study sites
- 5
- Registry updated
- 24 September 2026
Can you take part?
- Aged 18 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Above 18 years old * Diagnosed with a chronic respiratory disease and followed up in one of the participating Belgian hospitals * Performed a complete lung function test (spirometry, body plethysmography and diffusion capacity) at baseline * Have at least 3 historical spirometry measurements over a minimal time window of 2 years prior to inclusion * Planned routine follow-up within standard clinical care in one of the participating hospitals Exclusion Criteria: * Patients who have had a lung transplantation * Patients not being able to give consent to participate
What this study is about
In the sponsor’s own words, from the registry.
Currently, it remains unclear how to manage serial lung function measurements in a clinical setting. The investigators aimed to tackle this problem by developing a machine learning (ML) model that can accurately predict population and individual lung function trajectories. These predictions would enable the investigators to identify positive or negative deviations, thereby revealing unexpected disease patterns.
A prospective validation is needed that includes data on mortality, hospitalisations, emergency-room visits and patient-reported outcomes. Within this study, the goal is to validate the ML model with the data collected from this observational study.
Study sites(5)
UZ Antwerpen
Edegem, Belgium
Recruiting
Ziekenhuis Oost-Limburg
Genk, Belgium
Recruiting
UZ Gent
Ghent, Belgium
Recruiting
UZ Leuven
Leuven, Belgium
Recruiting
AZ Delta
Roeselare, Belgium
Recruiting
Showing 5 of 5 sites. 5 of the 5 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07419555. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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