Concurrent Exercise Effects in Post-Bariatric Patients
Effect of a Concurrent Exercise Program on Muscle Quality, Body Composition, Functional Response, and Quality of Life in Individuals Undergoing Bariatric Surgery: Protocol for a Randomized Controlled Clinical Trial
- Obesity & Overweight
- Post-bariatric Surgery
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- Universidad Autónoma de Chile
- Enrolment target
- 87
- Started
- 11 August 2025
- Main results due
- 31 December 2027
- Study sites
- 1
- Registry updated
- 25 September 2026
Can you take part?
- Ages 18 years to 60 years.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria * Adults aged 18-60 years. * Participants eligible for the institutional PAD (Pago Asociado a Diagnóstico) bariatric surgery program with medical indication for metabolic rehabilitation. * Undergoing sleeve gastrectomy or Roux-en-Y gastric bypass at Clínica BUPA Santiago. * Medical indication for metabolic rehabilitation. * Able and willing to provide written informed consent. Exclusion Criteria * Type 1 diabetes mellitus or type 2 diabetes mellitus with severe complications (including stage G4-G5 nephropathy, severe autonomic neuropathy, or high risk of exercise-related hypoglycemia). * Severe musculoskeletal disorders limiting participation in the exercise program. * Acute cardiovascular event within the previous 3 months or medical contraindication to supervised exercise. * Severe cardiorespiratory disease or dyspnea at rest or with minimal exertion. * Dependence on supplemental oxygen. * Bariatric surgery complications (e.g., leak, bleeding, stenosis, or intra-abdominal abscess). * Liver failure, kidney failure, or any other clinical condition compromising safe participation in the exercise program.
What this study is about
In the sponsor’s own words, from the registry.
This study aims to evaluate the effect of a 5-week concurrent exercise program (aerobic and resistance training) on muscle quality, body composition, functional response, and quality of life in individuals undergoing bariatric surgery.
This is a single-center, prospective, longitudinal, randomized controlled clinical trial with two parallel groups: an intervention group and a control group. A total of 87 adults aged 18 to 60 years who have undergone sleeve gastrectomy or Roux-en-Y gastric bypass and have a medical indication for metabolic rehabilitation will be recruited.
The intervention group will participate in a structured, semi-supervised concurrent exercise program for 5 weeks, consisting of two in-person sessions per week (10 sessions in total), whereas the control group will continue receiving usual kinesiology care and standard clinical management according to the institutional rehabilitation protocol at Clínica BUPA Santiago. All participants will be assessed at two time points: baseline, during the fourth postoperative week, and at week 7.
The primary outcome will be the change in rectus femoris muscle quality assessed by ultrasound (echo intensity). Secondary outcomes will include body composition (bioelectrical impedance analysis), functional response (One-minute Sit-to-Stand Test), and quality of life (Moorehead-Ardelt II questionnaire).
Additionally, adherence to the exercise program in the intervention group will be assessed as the percentage of attendance at supervised exercise sessions, and its association with the magnitude of changes in study outcomes will be explored.
The findings are expected to provide clinically relevant evidence regarding the effectiveness of exercise during the early postoperative period and to contribute to the optimization of metabolic rehabilitation strategies following bariatric surgery.
Study sites(1)
Clínica BUPA, Santiago
Santiago, Santiago Metropolitan, Chile
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07423780. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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