Language Network Prehab Via fMRI Neurofeedback
fMRI Neurofeedback for Prehabilitation of the Language Network in Patients Undergoing Radical Glioma Surgery
- Glioma
- Glioma Surgery
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- Yale University
- Enrolment target
- 4
- Started
- 1 August 2026
- Main results due
- December 2026
- Study sites
- 1
- Registry updated
- 29 September 2026
Can you take part?
- Aged 18 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Diagnosis of WHO grade II-III glioma involving eloquent language cortex * Scheduled for surgical resection * MRI-compatible * Ability to perform the simple language tasks required for fMRI and neurofeedback * Residence within 2 hours of Yale MRRC and ability and willingness to make multiple visits for study participation Exclusion Criteria: * Severe baseline aphasia precluding task performance * Contraindications to MRI * Significant cognitive/psychiatric comorbidity limiting compliance * Concurrent enrollment in other interventional trials * Claustrophobia of a degree that they cannot comfortably be scanned * Inability or unwillingness to understand or follow the instructions * Pregnancy or possible pregnancy
What this study is about
In the sponsor’s own words, from the registry.
This is an interventional neuroimaging study that will examine whether fMRI neurofeedback can shift language network activity away from regions affected by glioma prior to surgery.
Study sites(1)
Yale School of Medicine
New Haven, Connecticut, United States
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07488780. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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