NCT07512167From ClinicalTrials.govRecruiting

Tetanus Severity Score for Prediction of Mortality in Manifest Tetanus

Comparison of Three Scoring Systems for Prediction of Mortality in Patients Admitted to the Intensive Care Unit With Manifest Tetanus

Tetanus, Manifest

At a glance

Phase: Phase not stated
Study type: Observational
Sponsor: Ain Shams University
Enrolment target: 115
Started: 15 April 2026
Main results due: 15 October 2026
Study sites: 1
Registry updated: 29 September 2026

Can you take part?

Aged 18 years and over.
Open to any sex.
You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria

Inclusion criteria:

* Adults (age 18 years old or more).
* Any sex (male or female), regardless of gender identity.
* Diagnosis of manifest tetanus according to the WHO criteria (https://www.who.int/news-room/fact-sheets/detail/tetanus), that is the presence of one or both of the following criteria with or without the history of specific wound or injury:

  * Sustained spasm of the facial muscles in which person appears grinning.
  * Painful muscular contractions

Exclusion criteria:

* Age \< 18 years.
* Absent criteria of manifest tetanus, as per the WHO criteria (https://www.who.int/news-room/fact-sheets/detail/tetanus).
* Incomplete medical record with missing data required to calculate the Tetanus Severity Score, Philips Score, or Dakar score.
* Incomplete medical record with missing data regarding the primary outcome measure (survival to hospital discharge or in-hospital mortality).

What this study is about

In the sponsor’s own words, from the registry.

Three scoring systems will be applied to patients suffering from manifest tetanus and will be related to mortality.

Study sites(1)

Ain Shams University Hospitals & Demanhour Fever Hospital
Cairo, Cairo Governorate, Egypt
Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT07512167. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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