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NCT07532226From ClinicalTrials.govRecruiting

A Study of Guselkumab Treatment Persistence in Psoriatic Arthritis Participants

A Real-World, Prospective Study of Guselkumab Treatment Persistence in Psoriatic Arthritis Patients

  • Arthritis, Psoriatic

At a glance

Phase
Phase not stated
Study type
Observational
Sponsor
Janssen-Cilag Ltd.
Enrolment target
200
Started
17 April 2026
Main results due
10 December 2029
Study sites
1
Registry updated
25 September 2026

Can you take part?

  • Aged 18 years and over.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion criteria:

* Have a confirmed diagnosis of psoriatic arthritis (PsA) as determined by a rheumatologist with reference to ClASsification criteria for Psoriatic ARthritis (CASPAR)
* Start guselkumab as a first, second, third, or fourth line of disease-modifying antirheumatic drug (bDMARD) therapy for the indication of PsA as part of standard clinical practice at the time of enrollment into the observational study
* Initiating guselkumab treatment according to Summary of Product Characteristics (SmPC) indication
* The treatment decision must be taken by the participating rheumatologist prior to, and independently of the patient's inclusion into the study, following clinical practice in accordance with local and overarching guidelines and local regulations
* Must have received the information note, given his/her oral agreement and has not objected to the collection of his/her data in accordance with French requirements

Exclusion Criteria:

* Have already taken a specific interleukin-23 inhibitor (IL-23i) treatment.
* Are receiving combination therapy: 2 or more targeted therapies (biotherapy, Janus kinase \[JAK\] inhibitor, phosphodiesterase 4 (PDE4) inhibitor) indicated for PsA/PsO at the same time
* Has a contra-indication to guselkumab according to the SmPC (for hypersensitivity or due to active clinically important infection, example active tuberculosis)
* Unwilling or unable to participate in long-term data collection
* Received an investigational drug (including investigational vaccines) or used an invasive investigational medical device within 30 days before the start of the study ( that is, signing of informed consent)
* Currently enrolled in any interventional study or any Janssen-Cilag France-sponsored observational clinical study
* Is under guardianship or curatorship, judicial protection, future protection mandate or under family authorization

What this study is about

In the sponsor’s own words, from the registry.

This observational study aims to assess the 1-year persistence of guselkumab in adult patients with psoriatic arthritis (an inflammatory disease that affects the joints in participants with psoriasis, a skin condition that causes red, scaly patches).

Study sites(1)

  • Hopital Roger Salengro - CHU Lille

    Lille, France

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT07532226. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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A Study of Guselkumab Treatment Persistence in Psoriatic Arthritis Participants | Trialion