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NCT07582783From ClinicalTrials.govRecruiting

A Study of Persistence to Guselkumab Treatment in Participants With Moderate-to-Severe Plaque Psoriasis in Romania

Persistence to Treatment With Guselkumab in Bio-Naive Patients With Moderate-to-Severe Plaque Psoriasis: A Romanian Non-Interventional Multi-center Observational Study

  • Psoriasis

At a glance

Phase
Phase not stated
Study type
Observational
Sponsor
Janssen Research & Development, LLC
Enrolment target
200
Started
15 May 2026
Main results due
15 September 2028
Study sites
20
Registry updated
25 September 2026

Can you take part?

  • Aged 18 years and over.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion criteria:

* Has a confirmed diagnosis of moderate-to-severe plaque psoriasis
* Participant must sign an informed consent form allowing source data verification in accordance with local requirements
* Is able to read, understand, and complete the patient reported outcomes (PRO) instruments in local language and comply with completion of all PRO instruments
* No previous exposure to biological treatment, including guselkumab (bio-naive patient)
* Intended for the treatment with guselkumab according to the approved indication

Exclusion criteria:

* Meets any of the contraindications according to the latest version of the locally approved summary of product characteristics (SmPC)
* Is pregnant or lactating
* Current or recent (in the last 30 days prior to first SC dose of guselkumab) participation in any interventional study with investigational product.
* Currently enrolled in another observational study sponsored or managed by a Johnson \& Johnson company

What this study is about

In the sponsor’s own words, from the registry.

This study aims to assess the proportion of participants with moderate-to-severe plaque psoriasis who continue treatment with guselkumab over a two-year period.

Study sites(20)

  • Mihaila G. Georgiana - Cabinet Medical Individual Dermatovenerologie

    Bârlad, Romania

    Recruiting

  • Qualimed SRL

    Brasov, Romania

    Recruiting

  • Spitalul Universitar de Urgenta Elias, Clinica de Cardiologie

    Bucharest, Romania

    Recruiting

  • Spitalul Clinic Colentina 1

    Bucharest, Romania

    Recruiting

  • Spitalul Clinic Colentina

    Bucharest, Romania

    Recruiting

  • Alin Nicolescu Medic Primar Dermato Venerologie

    Bucharest, Romania

    Recruiting

  • OptiDerm Estet

    Bucharest, Romania

    Recruiting

  • Spitalul Clinic Judetean de Urgenta Cluj Napoca

    Cluj-Napoca, Romania

    Recruiting

  • Ambulator Specialitate Sp Militar de Urgenta Dr Constantin Papilian Cluj Napoca

    Cluj-Napoca, Romania

    Recruiting

  • Innovative Derm SRL

    Constanța, Romania

    Recruiting

  • MC Medica SRL

    Craiova, Romania

    Recruiting

  • Policlinica Dr.Corbeanu

    Craiova, Romania

    Recruiting

  • Policlinica Top Med Buna Vestire

    Craiova, Romania

    Recruiting

  • Derma Lux SRL

    Iași, Romania

    Recruiting

  • Spitalul Clinic Judetean de Urgenta Bihor

    Oradea, Romania

    Recruiting

  • Derma Lux SRL 1

    Reghin, Romania

    Recruiting

  • Evaderm Health SRL

    Slatina, Romania

    Recruiting

  • Spitalul Judetean de Urgenta 'Sf.Ioan cel Nou', Sectia Oncologie

    Suceava, Romania

    Recruiting

  • Clinica Cabimed

    Targu Mureș, Romania

    Recruiting

  • Dr Tirziu Dermato Chirurgie SRL

    Timișoara, Romania

    Recruiting

Showing 20 of 20 sites. 20 of the 20 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT07582783. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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A Study of Persistence to Guselkumab Treatment in Participants With Moderate-to-Severe Plaque Psoriasis in Rom | Trialion