CAYA Cancer Prospective Cohort Study
Improving Cancer Outcomes for Children, Adolescents, and Young Adults: A Multicenter Prospective Cohort Study on Treatment Failure and Toxicity in Low- and Middle-Income Countries.
- Cancer
- Pediatric Cancer
- Lymphoblastic Lymphoma (LBL)
- Acute Lymphoblastic Leukemia (ALL)
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- Resonance, Inc.
- Enrolment target
- 6,000
- Started
- 18 September 2026
- Main results due
- 11 November 2032
- Study sites
- 6
- Registry updated
- 29 September 2026
Can you take part?
- Ages 0 years to 21 years.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: Subjects must meet all the following criteria to be included in this study: 1. Age 0 to 21 years at study enrollment. 2. Diagnosed with cancer and receiving active treatment or undergoing follow-up at the participating sites. a. Note: Patients seen solely for consultation or diagnostic evaluations without subsequent treatment and those who have been off treatment for more than 5 years and are seen only for survivorship follow-up are not considered as meeting this criterion. 3. Willingness to provide informed consent/assent. For minors incapable of providing assent, or individuals unable to provide consent, consent must be obtained from a legal representative and in accordance with local requirements. Exclusion Criteria: Subjects meeting any of the following criteria must be excluded from this study: 1\. Any medical or psychological condition that, in the investigator's opinion, might compromise the ability of the patient to provide assent/informed consent/assent.
What this study is about
In the sponsor’s own words, from the registry.
Cancer is a leading cause of illness and death among children, adolescents, and young adults(CAYAs), especially in low- and middle-income countries(LMICs), where access to timely diagnosis and treatment is often limited. As a result, patients in these settings may experience higher rates of treatment complications, interruptions, and poorer outcomes compared with those in high-income countries (HICs).
This is a prospective, multicenter observational study that will follow children, adolescents, and young adults(CAYAs) with cancer who are receiving routine care at participating hospitals in low - and middle - income countries(LMICs). The study does not involve experimental treatments or changes to standard medical care. Information will be collected from medical records and from questionnaires that address access to care and social factors affecting treatment.
By describing treatment outcomes and the challenges patients and families face during cancer care, this study aims to provide data that can help inform future efforts to improve access to care and cancer outcomes in resource-limited settings.
Study sites(6)
Yeolyan Center for Cancer and Blood Disorders
Yerevan, Armenia
Not yet recruiting
The Children's Cancer Hospital Egypt 57357
Cairo, Egypt
Not yet recruiting
Fundación Ayúdame a Vivir
San Salvador, El Salvador
Not yet recruiting
Unidad Nacional de Oncología Pediátrica (UNOP)
Guatemala City, Guatemala
Recruiting
Hospital Mario Catarino Rivas
San Pedro Sula, Honduras
Not yet recruiting
Hospital Escuela
Tegucigalpa, Honduras
Not yet recruiting
Showing 6 of 6 sites. 1 of the 6 sites on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07632014. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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