Venous Thromboembolism (VTE) Prophylaxis With REGN7508 and REGN9933 in Adult and Adolescent Participants With a Peripherally Inserted Central Catheter (PICC)

Key Inclusion Criteria:

1. Is undergoing PICC placement for Intravenous (IV) administration of clinically indicated medications, including chemotherapy, antibiotics, TPN, and/or other indications as described in the protocol
2. Has Eastern Cooperative Oncology Group Performance (ECOG) Status ≤3 or equivalent functional status as described in the protocol
3. Has International Normalization Ratio (INR) and aPTT values no more than 25% above the upper limit as described in the protocol
4. Weighs at least 40 kg during the screening period

Key Exclusion Criteria:

1. Has a history of prior venous thrombosis in the arm and/or ipsilateral thoracic central veins in which the PICC is to be placed
2. Has acute leukemia, myelodysplastic syndrome, or primary and secondary myelofibrosis
3. Has unresected luminal gastrointestinal (GI) (including esophageal) or unresected genitourinary (GU) malignancy
4. Has current or history of known brain tumors or brain metastases
5. Has any major cardiovascular event within approximately the past 30 days prior to study administration
6. Pre-existing central venous catheter or indwelling spinal or epidural catheter during the screening period

Note: Other Protocol Defined Inclusion/ Exclusion Criteria Apply