The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Chronic Ankle Instability
Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training on Dynamic Balance, Functional Instability and Neurocognitive Performance in Amateur Athletes With Chronic Ankle Instability
- Ankle Sprains
- Ankle Sprain Strain
- Ankle Inversion Sprain
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- Bahçeşehir University
- Enrolment target
- 56
- Started
- 22 July 2026
- Main results due
- 22 July 2027
- Study sites
- 1
- Registry updated
- 29 September 2026
Can you take part?
- Ages 18 years to 35 years.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Being between 18 and 35 years of age. * Being classified as a Tier 2 athlete according to the McKay et al. Participant Classification Framework (trained/developmental level). * Having a history of at least one lateral ankle sprain (LAS) occurring at least 12 months before enrollment, resulting in swelling, pain, and functional impairment, and followed by persistent instability. * Having the most recent ankle sprain at least 3 months before study enrollment. * Having a history of recurrent ankle sprains or episodes of "giving way." * Having a diagnosis of unilateral chronic ankle instability (CAI). * Having a Cumberland Ankle Instability Tool - Turkish Version (CAIT-T) score of ≤24. * Having a Foot and Ankle Ability Measure (FAAM) score of \<90%. * Having a Foot and Ankle Ability Measure Sports subscale (FAAM-S) score of \<80%. * A side-to-side difference of ≥2.5 cm in Weight-Bearing Lunge Test distance, with the affected side demonstrating less dorsiflexion than the unaffected side. Exclusion Criteria: * History of acute lateral ankle sprain within the last 3 months. * History of lower extremity surgery. * History of acute injury to other musculoskeletal structures of the lower extremity joints within the last 3 months that affected joint integrity and function and caused interruption of desired physical activity for at least one day. * History of balance or vestibular disorders, including cerebellar, vestibular, cochlear, or inner ear dysfunction. * Visual problems that may affect the administration or interpretation of the Dynamic Visual Acuity Test, including a history of amblyopia, diplopia, or significant visual loss. * Persistent symptoms related to a previous concussion or traumatic brain injury.
What this study is about
In the sponsor’s own words, from the registry.
Chronic ankle instability (CAI) is a common condition after lateral ankle sprain. CAI is characterized by mechanical and/or functional instability, or recurrent episodes of "giving way," persisting for at least 12 months after the initial injury, and is associated with limitations in activity and participation. In amateur athletes, CAI may be overlooked or undertreated, although sport-specific activities require rapid integration of visual, vestibular, somatosensory, and cognitive information.
Postural stabilization training is commonly used to improve balance and neuromuscular control in individuals with CAI. However, individuals with CAI may show increased reliance on visual information and altered visual-vestibular sensory reweighting during postural control tasks. The vestibulo-ocular reflex (VOR) contributes to gaze stability and visual clarity during head movements and may also be related to neurocognitive processes such as attention and processing speed. This study is designed as a randomized controlled, prospective, parallel-group, pretest-posttest design trial to investigate whether VOR exercises added to postural stabilization training improve dynamic balance, functional instability, and neurocognitive performance in amateur athletes with CAI.
Study sites(1)
Reset Fizyoterapi
Istanbul, Turkey (Türkiye)
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07728526. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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