Clinical and Brain Activity Assessment Before and After Physiotherapy in People With Chronic Non-specific Neck Pain
Predictors of Response After Physiotherapy Treatment in People With Chronic Non-specific Neck Pain
- Neck Pain Musculoskeletal
- Chronic Neck Pain
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- Ander Cervantes Benítez
- Enrolment target
- 100
- Started
- 21 March 2024
- Main results due
- March 2027
- Study sites
- 1
- Registry updated
- 25 September 2026
Can you take part?
- Aged 18 years and over.
- Open to any sex.
- Healthy volunteers can take part.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Chronic non-specific neck pain (\>3 months duration) * Willing and able to sign informed consent for study participation Exclusion Criteria: * Concomitant neurological or psychiatric disease apart from depression (especially severe mental disorder or psychopathology) * Regular (daily) intake of benzodiazepines * Signs of severe disease, cervical myelopathy, tumour, rheumatic diseases or a neurological pathology of central origin * Neck pain of traumatic origin or as a result of whiplash * Previous surgical intervention of the cervical spine
What this study is about
In the sponsor’s own words, from the registry.
The goal of this clinical trial is to investigate whether electroencephalographic features are associated with the multidimensional clinical characteristics of adults with chronic non-specific neck pain and whether clinical and brain function measures change following physiotherapy. Participants with chronic non-specific neck pain will receive six weekly treatment sessions consisting of a manual physiotherapy and neck-specific exercise programme, including a home exercise programme. Clinical, psychophysical, and 64-channel electroencephalographic assessments will be performed at baseline and approximately one week after completion of the intervention. Clinical outcomes will also be reassessed 12 weeks after the last treatment session. Electroencephalographic recordings will be obtained while participants are seated comfortably and instructed to remain relaxed. EEG-derived measures will be examined in relation to pain intensity, neck-related disability, psychological and cognitive-affective factors, sleep quality, and psychophysical pain responses. Healthy participants without chronic neck pain will undergo a comparable baseline assessment to provide reference data for the interpretation of brain function in the clinical group.
Study sites(1)
Ander Cervantes Benítez
San Sebastián, Guipuzcoa, Spain
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07756229. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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