Long-Term Study of COVID-19 Infection and Long COVID
Longitudinal Study of Patients With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Post-Acute Sequelae of COVID-19 (PASC)
- SARS CoV-2 Post-Acute Sequelae
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- University of North Carolina, Chapel Hill
- Enrolment target
- 500
- Started
- 4 September 2024
- Main results due
- 31 December 2028
- Study sites
- 1
- Registry updated
- 28 September 2026
Can you take part?
- Ages 18 years to 75 years.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Age 18 to 75 years. * Previous laboratory-confirmed SARS-CoV-2 infection. * Willing and able to provide informed consent. * Able to complete study questionnaires and study procedures. Exclusion Criteria: * Current severe periodontal disease with bleeding gums. * Current oral herpes flare, aphthous ulcer, or oral candidiasis (thrush). * Oral viral or bacterial infection within the previous 30 days. * Dry mouth that would prevent adequate saliva collection. * Active alcohol or drug abuse. * Medical or genetic syndrome or developmental delay that would prevent completion of study procedures or questionnaires.
What this study is about
In the sponsor’s own words, from the registry.
This study will examine how common Long COVID is and how symptoms may persist over time in people who have previously had COVID-19. Researchers will collect information about participants' health and symptoms through questionnaires and may collect saliva and other non-invasive oral samples. The study will also examine biological factors in these samples that may be associated with persistent symptoms. The goal is to better understand why some people develop Long COVID and identify factors that may help predict who is more likely to experience persistent symptoms.
Study sites(1)
University of North Carolina
Chapel Hill, North Carolina, United States
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07781501. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
Not the right study?
Answer three questions and see the studies recruiting near you, in plain language.
Find a study for me