Comparison of ACUVUE® OASYS MAX 1-Day Multifocal and DAILIES® AquaComfort Plus® Multifocal
- Visual Acuity
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- Johnson & Johnson Vision Care, Inc.
- Enrolment target
- 150
- Started
- 10 September 2026
- Main results due
- 11 December 2026
- Study sites
- 11
- Registry updated
- 29 September 2026
Can you take part?
- Ages 40 years to 70 years.
- Open to any sex.
- Healthy volunteers can take part.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Potential subjects must satisfy all of the following criteria to be enrolled in the study: 1. Read, understand, and sign the STATEMENT OF INFORMED CONSENT and receive a fully executed copy of the form. 2. Appear able and willing to adhere to the instructions set forth in this clinical protocol. 3. Be at least 40 years of age and not greater than 70 years of age at the time of consent. 4. Own a wearable pair of spectacles if required for their distance vision. 5. Be an adapted soft contact lens wearer in both eyes (i.e. worn lenses a minimum of 2 days per week for at least 6 hours per wear day, for 30 days or more duration). 6. Either already be wearing a presbyopic contact lens correction (e.g., reading spectacles over contact lenses, multifocal or monovision contact lenses, etc.) or if not respond positively to at least one symptom on the "Presbyopic Symptoms Questionnaire". 7. The subject's distance spherical equivalent refraction (vertex corrected if ≥-4.25 D) must be in the range of -1.50 D to -5.50 D in each eye. 8. The subject's refractive cylinder must be ≤0.75 D in each eye. 9. The subject's ADD power must be in the range of +0.75 D to +2.50 D. 10. The subject must have distance best corrected visual acuity of 0.0 logMAR (20/20 Snellen, 5.0 on the China standard 5-point logMAR visual acuity scale) or better in each eye. Potential subjects who meet any of the following criteria will be excluded from participating in the study: 1. Be currently pregnant or lactating. 2. Have any active or ongoing ocular or systemic allergies that may interfere with contact lens wear. 3. Have been diagnosed with diabetes. 4. Have any active or ongoing systemic disease, autoimmune disease, or use of medication, which may interfere with contact lens wear. This may include, but not be limited to, hyperthyroidism, Sjögren's syndrome, xerophthalmia, acne rosacea, Stevens-Johnson syndrome, and immunosuppressive diseases or any infectious diseases (e.g. hepatitis, tuberculosis). 5. Have any previous, or planned, ocular or intraocular surgery (e.g. radial keratotomy, PRK, LASIK, lid procedures, dacryocystorhinostomy, peripheral iridotomy/iridectomy, cataract surgery, retinal surgery, etc.). 6. Have a history of amblyopia, strabismus or binocular vision abnormality. 7. Use of any of the following medications within 1 week prior to enrollment: oral retinoid, oral tetracyclines, anticholinergics, oral phenothiazines, oral/inhaled corticosteroids. 8. Use of any ocular medication. 9. Have a history of herpetic keratitis. 10. Have a history of irregular cornea. 11. Have a history of pathological dry eye. 12. Have a history of glaucoma or glaucoma suspect. 13. Have a history of any retinal disease/condition that may interfere with any of the study assessments or are not stable and have potential to progress during the study. 14. Have participated in any contact lens or lens care product clinical trial within 15 days prior to study enrollment. 15. Be an employee (e.g., Investigator, Coordinator, Technician) or immediate family member of an employee (including partner, child, parent, grandparent, grandchild, sibling of the employee or their spouse) of the clinical site. 16. Have any known hypersensitivity or allergic reaction to sodium fluorescein. 17. Have Grade 3 or greater palpebral conjunctival observations or Grade 2 or greater slit lamp findings (e.g. corneal edema, corneal vascularization, corneal staining, bulbar injection, etc.) on the ISO 11980 classification scale, or any other corneal or ocular abnormalities which would contraindicate contact lens wear. 18. Have any current ocular infection or inflammation. 19. Have intraocular pressure in one or both eyes \>21mmHg 20. Have signs of any retinal disease/conditions that may interfere with any of the study assessments or are not stable and have potential to progress during the study.
What this study is about
In the sponsor’s own words, from the registry.
This study is a 4-visit, multi-site, prospective, controlled, randomized, single-masked (subjects), two-arm parallel group, bilateral, dispensing clinical trial to compare the performance of the Test lens to the Control lens in terms of safety and efficacy.
Study sites(11)
Pearson Research Center PA
Longwood, Florida, United States
Active, not recruiting
VisualEyes
Roswell, Georgia, United States
Recruiting
The Koetting Associates
St Louis, Missouri, United States
Recruiting
Spectrum Eyecare
Jamestown, New York, United States
Recruiting
Center for Ophthalmic and Vision Research/Eye Associates of New York
Manhattan, New York, United States
Recruiting
Sacco Eye Group
Vestal, New York, United States
Recruiting
Dr. David W. Ferris & Associates
Warwick, Rhode Island, United States
Recruiting
Total Eye Care
Memphis, Tennessee, United States
Recruiting
Paradigm Research Center, LLC
Houston, Texas, United States
Recruiting
Tyler Eye Associates
Tyler, Texas, United States
Recruiting
Botetourt Eyecare, LLC
Salem, Virginia, United States
Recruiting
Showing 11 of 11 sites. 10 of the 11 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07788521. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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