Post-Vasectomy Pain Study
A Randomized Controlled Trial of Post-vasectomy Pain Management
- Vasectomy
- NSAIDs
- Post-operative Care
At a glance
- Phase
- Phase 1
- Study type
- Interventional
- Sponsor
- Columbia University
- Enrolment target
- 200
- Started
- 10 September 2026
- Main results due
- 31 December 2030
- Study sites
- 2
- Registry updated
- 24 September 2026
Can you take part?
- Ages 18 years to 65 years.
- Men only.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: \- Consent for vasectomy Exclusion Criteria: * History of kidney or liver disease * History of chronic pain condition * History of drug abuse
What this study is about
In the sponsor’s own words, from the registry.
This is a prospective four-armed unblinded randomized controlled trial to assess four different potential post-operative treatment options for men who undergo a vasectomy. The aims of this study are:
* To determine whether the addition of nonsteroidal anti-inflammatory drugs (NSAIDs) to acetaminophen results in improved pain after vasectomy; * To determine whether the addition of opioid pain medication to acetaminophen and/or NSAIDs results in improved pain after vasectomy; * To determine whether the use of NSAIDs for post-operative pain management increases risk of hematoma after vasectomy.
Study sites(2)
Columbia University Medical Center/ New York Presbyterian Hospital
New York, New York, United States
Recruiting
New York-Presbyterian The One
White Plains, New York, United States
Recruiting
Showing 2 of 2 sites. 2 of the 2 sites on this study are recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07824258. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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