Demedetomidine and Remifentanil in Electroconvulsive Therapy (ECT)
Comparison of Three Different Anesthetic Methods in ECT
- Hemodynamic Response
At a glance
- Phase
- Phase 4
- Study type
- Interventional
- Sponsor
- Inonu University
- Enrolment target
- 24
- Started
- 21 September 2026
- Main results due
- 1 February 2027
- Study sites
- 1
- Registry updated
- 29 September 2026
Can you take part?
- Ages 18 years to 60 years.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Upremedicated ASA I-II (American Society of Anesthesiologists's physical status) patients, * Patients scheduled for six ECT sessions for a variety of psychiatric conditions Exclusion Criteria: * refusal to participate, * age below 18 or above 60 years * pregnancy * asthma * current use of β-adrenergic blockers * myocardial infarction within the previous six months * atrial fibrillation or atrial flutter, * heart block * a known personal or family history of hypersensitivity to any of the study drugs
What this study is about
In the sponsor’s own words, from the registry.
Electroconvulsive therapy (ECT) is a treatment modality that induces therapeutic seizures through electrical stimulation for the management of certain psychiatric disorders. Nearly all ECT procedures are performed under general anesthesia. However, ECT is commonly associated with acute hyperdynamic responses immediately following electrical stimulation, including transient hypertension and tachycardia. These acute hemodynamic changes may pose significant risks, particularly in patients with ischemic heart disease, hypertension, or cerebrovascular disease. Therefore, the hemodynamic response, seizure quality, and recovery profile are critical factors influencing the choice of anesthetic and adjuvant agents. The primary goal of anesthesia for ECT is to maintain hemodynamic stability without compromising seizure duration or quality while ensuring rapid and safe recovery
Study sites(1)
Inonu Universitesi Turgut Ozal Tıp Merkezi
Malatya, Battalgazi, Turkey (Türkiye)
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07824817. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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