Lower Body Negative Pressure to Validate Physiological Monitors
- Physiological Stress
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- Mayo Clinic
- Enrolment target
- 50
- Started
- 30 September 2026
- Main results due
- 28 September 2028
- Study sites
- 1
- Registry updated
- 24 September 2026
Can you take part?
- Ages 18 years to 55 years.
- Open to any sex.
- Healthy volunteers can take part.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Non-obese (BMI\<30) * Non-smokers * Free of any systemic diseases including hypertension, diabetes, coronary artery disease, neurologic disease, or any other major medical co-morbidity. * Women will be either surgically sterilized or non-pregnant as determined by a urine pregnancy test (within 48 hours of the study day) Exclusion Criteria: * Individuals taking GLP-1 medications or compounds known to affect responses of the autonomic nervous system to orthostatic stress (e.g., β-blockers) * Pregnant women
What this study is about
In the sponsor’s own words, from the registry.
The purpose of this research is to test the accuracy of non-invasive physiological monitors while the body responds to different levels of lower body negative pressure (LBNP).
Study sites(1)
Mayo Clinic
Rochester, Minnesota, United States
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07840144. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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