Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation Using Customized Porous Zirconia Shell
Histological and Histomorphometric Assessment With Inflammatory Profile Analysis of Bone Tissue After Horizontal Ridge Augmentation of the Lower Posterior Mandible Using a Novel Customized Porous Zirconia Shell Technique: Clinical Case Study
- Alveolar Bone Loss
- Alveolar Ridge Deficiency
At a glance
- Phase
- Phase not stated
- Study type
- Interventional
- Sponsor
- Mohammed Mahmoud Abed
- Enrolment target
- 10
- Started
- 15 March 2025
- Main results due
- 1 May 2027
- Study sites
- 1
- Registry updated
- 25 September 2026
Can you take part?
- Aged 21 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: * Adults older than 21 years * Horizontal bone defect (Seibert Class I) in the posterior mandible * Enough inter-arch space for an implant-supported prosthesis * Motivated to receive the treatment * Good oral hygiene Exclusion Criteria: * Systemic conditions that could interfere with healing * Pregnancy * Smoking * Poor oral hygiene
What this study is about
In the sponsor’s own words, from the registry.
The goal of this clinical study is to learn whether a custom-made porous zirconia shell can support good-quality new bone when widening the lower back jaw before dental implant placement. The study includes adults whose jawbone in this area is too narrow for implants (Seibert Class I defects).
The main question it aims to answer is: What is the quality of the new bone formed under a porous zirconia shell, and how much inflammation does the tissue show?
Participants will:
* Receive gum treatment and a CBCT scan before surgery * Have bone augmentation surgery, in which a digitally designed porous zirconia shell is fixed over a mixture of their own bone and bovine bone graft * Return after 2 weeks for suture removal and a check of the wound * Return after 6 months for a CBCT scan, removal of the shell, collection of a small bone sample (biopsy), and dental implant placement
Study sites(1)
October University for Modern Sciences and Arts (MSA), Faculty of Dentistry
Giza, Giza Governorate, Egypt
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07841158. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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