Cardiorespiratory Fitness After Lobectomy Versus Sublobar Resection
Impact of Lobectomy Versus Sublobar Resection on Cardiorespiratory Fitness: An Observational Study Based on Cardiopulmonary Exercise Testing
- Lung Cancer (NSCLC)
At a glance
- Phase
- Phase not stated
- Study type
- Observational
- Sponsor
- Tongji Hospital
- Enrolment target
- 604
- Started
- 1 August 2022
- Main results due
- 31 July 2027
- Study sites
- 1
- Registry updated
- 25 September 2026
Can you take part?
- Aged 18 years and over.
- Open to any sex.
- You need the condition being studied — healthy volunteers are not accepted.
These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.
Read the full eligibility criteria
Inclusion Criteria: 1\. Able to understand the study and provide written informed consent. 2. Considered able to tolerate surgical treatment, including segmentectomy, lobectomy, or wedge resection, following preoperative assessment, including cardiac and pulmonary function testing. \- Exclusion Criteria: 1. Pregnant or breastfeeding. 2. Any absolute contraindication to CPET. 3. A history of severe heart disease, heart failure, myocardial infarction, or an episode of angina within the previous 3 months. 4. A cerebrovascular event, including cerebral infarction or cerebral hemorrhage, within the previous 3 months. 5. A psychiatric illness that prevents communication. 6. Unable to cooperate with the examinations. -
What this study is about
In the sponsor’s own words, from the registry.
This observational study will compare changes in cardiorespiratory fitness after lobectomy and sublobar resection. Sublobar resection includes segmentectomy and wedge resection. Patients who can undergo pulmonary resection and meet the eligibility criteria will be studied during routine clinical care; the research will not assign the surgical procedure or add a study-specific intervention.
Cardiopulmonary exercise testing (CPET) and pulmonary function testing will be performed before surgery and at routine follow-up visits 6 and 12 months after surgery. Changes from the preoperative assessment will be compared within each surgical group and between the two groups. The study will also examine the relationship between CPET measurements and postoperative complications.
Study sites(1)
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
Recruiting
Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.
Source: ClinicalTrials.gov record NCT07841249. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.
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