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NCT07841470From ClinicalTrials.govRecruiting

Corneal Crosslinking for Treatment of Progressive Keratoconus or Corneal Ectasia

Corneal Crosslinking for Treatment of Progressive Keratoconus or Ectasia: Randomized Comparison of Pulsed vs. Non-pulsed Treatment

  • Keratoconus
  • Corneal Ectasia

At a glance

Phase
Phase 2
Study type
Interventional
Sponsor
Price Vision Group
Enrolment target
500
Started
1 October 2025
Main results due
31 December 2030
Study sites
1
Registry updated
25 September 2026

Can you take part?

  • Ages 10 years to 90 years.
  • Open to any sex.
  • You need the condition being studied — healthy volunteers are not accepted.

These are the headline rules only. Every study has a longer list, and whether you are eligible is decided by the research team at the site — never by this page.

Read the full eligibility criteria
Inclusion Criteria:

* Diagnosis of keratoconus or corneal ectasia
* Provision of written informed consent

Exclusion Criteria:

* Previous ocular condition in the study eye that may predispose for future complications including history of corneal disease (e.g., herpes simplex, herpes zoster keratitis, recurrent erosion syndrome, corneal melt, corneal dystrophy, etc.)
* Clinically significant corneal scarring in the proposed treatment zone
* History of chemical injury or delayed epithelial healing in the study eye
* Known sensitivity to study medication
* A current condition, including clinically significant dry eyes or use of medications know to induce dry eye symptoms, that, in the treating physician's opinion, would interfere with or prolong epithelial healing
* Pregnancy (including plan to become pregnant) or lactation during the course of the study

What this study is about

In the sponsor’s own words, from the registry.

This randomized study compares 2 variations of corneal crosslinking for treatment of keratoconus or corneal ectasia.

Study sites(1)

  • Price Vision Group

    Indianapolis, Indiana, United States

    Recruiting

Showing 1 of 1 sites. 1 of the 1 site on this study is recruiting right now — a site can stop enrolling while the study as a whole is still open.

Source: ClinicalTrials.gov record NCT07841470. Trialion does not run this study, is not paid to refer anyone to it, and cannot enrol you. Eligibility is always decided by the research team at the site.

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Corneal Crosslinking for Treatment of Progressive Keratoconus or Corneal Ectasia | Trialion